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Supporting Gladstone
Publications 1994-1996
  • Tie F, Adya N, Greene WC, Giam C-z. Interaction of the human T-lymphotropic virus type 1 tax dimer with CREB and the viral 21-base-part repeat. J. Virol. 70(12):8368–8374, 1996.
  • Béraud C, Greene WC. Interaction of HTLV-I tax with the human proteasome: Implications for NF-kB induction. J. Acquired Immune Defic. Syndr. Hum. Retrovirol. 13(S1):S76–S84, 1996.
  • Geleziunas R, Miller MD, Greene WC. Unraveling the function of HIV Type 1 Nef. AIDS Res. Hum. Retroviruses 12(17):1579–1582, 1996.
  • Shapiro VS, Mollenauer MN, Greene WC, Weiss A. c-Rel regulation of IL-2 gene expression may be mediated through activation of AP-1. J. Exp. Med. 184(5):1663–1669, 1996.
  • Greene WC. Denying HIV safe haven. N. Eng. J. Med. 334(19):1264–1265, 1996.
  • Kim JH, McLinden RJ, Mosca JD, Vahey MT, Greene WC, Redfield RR. Inhibition of HIV replication by sense and antisense Rev response elements in HIV-based retroviral vectors. J. Acquired Immune Defic. Syndr. Hum. Retrovirol. 12(4):343–351, 1996.
  • Gaffen SL, Lai SY, Ha M, Liu X, Hennighausen L, Greene WC, Goldsmith MA. Distinct tyrosine residues within the interleukin-2 receptor b chain drive signal transduction specificity, redundancy, and diversity. J. Biol. Chem. 271:21381–21390, 1996.
  • Liu KD, Greene WC, Goldsmith MA. The a chain of the IL-2 receptor determines the species specificity of high-affinity IL-2 binding. Cytokine 8(8):613–621, 1996.
  • Evans GA, Goldsmith MA, Johnston JA, Weiler SR, Erwin R, Howard OM, Abraham RT, O'Shea JJ, Greene WC, Farrar WL. Analysis of IL-2-dependent signal transduction through the Shc/Grb2 adapter pathway: IL-2-dependent mitogenesis does not require Shc phosphorylation or receptor association. J. Biol. Chem. 270:28858–28863, 1996.
  • Lai SY, Xu W, Gaffen SL, Liu KD, Longmore GD, Greene WC, Goldsmith MA. The molecular role of the common gc subunit in signal transduction reveals functional asymmetry within multimeric cytokine receptor complexes. Proc. Natl. Acad. Sci. USA 93(1):231–5, 1996.
  • Miller MD, Greene WC. Is the Nef protein of HIV-1 required for pathogenesis? Trends Microbiol. 4:171–2, 1996.
  • Hsu DK, Hammes SR, Greene WC, Liu F-t. HTLV-I infection of human T lymphocytes induces expression of a b-galactose-binding lectin, galectin-3 (P). Am. J. Pathol. 148(5):1661–1670, 1996.
  • McGuire D, Greene WC. Neurological damage in HIV Infection. In: Lever AML (Ed.), The Molecular Biology of HIV/AIDS, John Wiley & Sons Ltd., 1996, pp. 127–142.
  • Sun S-c, Elwood J, Greene WC. Both amino- and carboxyl-terminal sequences within IkBa regulate its inducible degradation. Mol. Cell. Biol. 1:1058–1065, 1996.
  • Greene WC. Predicting progression to AIDS. Ann. Int. Med. 123(9):726–727, 1995.
  • Liu K, Lai S, Goldsmith MA, Greene WC. Identification of a variable region within the cytoplasmic tail of the IL-2 receptor b chain that is required for growth signal transduction. J. Biol. Chem. 270(38):22176–22181, 1995.
  • Goldsmith MA, Lai S, Xu W, Amaral M, Kuczek E, Parent L, Mills G, Tarr K, Longmore G, Greene WC. Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the b chain and non-tyrosine residues of the gc chain. J. Biol. Chem. 270(37):21729–21737, 1995.
  • Gaffen SL, Lai SY, Xu W, Gouilleux F, Groner B, Goldsmith MA, Greene WC. Signaling through the IL-2Rb chain activates a STAT-5-like binding activity. Proc. Natl. Acad. Sci. USA 92(16):7192–7196, 1995.
  • Goldsmith MA, Warmerdam M, Atchison R, Miller M, Greene WC. Dissociation of the CD4 downregulation and viral infectivity enhancement functions of HIV-1 nef. J. Virol. 69(7):4112–4121, 1995.
  • Goldsmith MA, Amaral MC, Greene WC. Ligand binding by the interleukin-2 receptor is modulated by intracellular determinants of the IL-2Rb chain. J. Immunol. 154:2033–2040, 1995.
  • Miller MD, Warmerdam MT, Page KA, Feinberg MB, Greene WC. Expression of the human immunodeficiency virus type 1 (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independent of gp160 or viral entry. J. Virol. 69(1):579–584, 1995.
  • Williamson P, Merida I, Greene WC, Gaulton G. The membrane proximal segment of the IL-2 receptor beta-chain acidic region is essential for IL2-dependent protein tyrosine kinase activation. Leukemia 1:S186–9, 1994.
  • Greene WC. Molecular insights into HIV-1 infection. In: Sande M, Volberding P (Eds.), The Medical Management of AIDS, Saunders Company, Philadelphia, 1994, pp. 22–37.
  • Miller MD, Feinberg MB, Greene WC. The Human Immunodeficiency Virus-1 nef gene acts as a positive viral infectivity factor. Trends Microbiol. 2(8):294–298, 1994.
  • Sun S-c, Elwood J, Beraud C, Greene WC. HTLV-1 tax activation of NF-kB/rel involves phosphorylation and degradation of IkBa and rel A (p65)-mediated induction of the c-rel gene. Mol. Cell. Biol. 14(11):7377–7384, 1994.
  • Goldsmith MA, Xu W, Amaral MC, Kuzcek ES, Greene WC. The cytoplasmic domain of the IL-2 receptor a chain contains both unique and functionally redundant signal transduction elements. J. Biol. Chem. 269(20):14698–14704, 1994.
  • Beraud C, Sun S-c, Ganchi P, Ballard DW, Greene WC. Human T-cell leukemia virus type I tax associates with and is negatively regulated by the NF-kB2 p100 gene product: Implications for viral latency. Mol. Cell. Biol. 14:1374–82, 1994.
  • Miller MD, Warmerdam MT, Gaston I, Greene WC, Feinberg MB. The HIV-1 nef gene product: a positive factor for viral replication in primary lymphocytes and macrophages. J. Exp. Med. 179:101–113, 1994.
  • Sun S-c, Ganchi PA, Beraud C, Ballard DW, Greene WC. Autoregulation of the NF-kB transactivator RelA (p65) by multiple cytoplasmic inhibitors containing ankyrin motifs. Proc. Natl. Acad. Sci. USA, 91:1346–50, 1994.
  • Ganchi PA, Sun S-c, Greene WC, Ballard DW. A novel NF-kB complex containing p65 homodimers: Implications for transcriptional control at the level of subunit dimerization. Mol. Biol. Cell 13(12) 7826–35, 1994.

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