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Supporting Gladstone
Publications 1991-1993
  • Greene WC, Miller MD, Warmerdam MT, Feinberg MB. The HIV-1 nef gene product: A positive factor for viral infection and replication in primary lymphocytes and macrophages. In: Girard M, Valette L (Eds.), Retroviruses of Human AIDS and Related Animal Diseases, Marnes-La-Coquette, Paris, France, 1993, pp. 227–242.
  • Stein B, Baldwin AS, Ballard DW, Angel P, Greene WC, Herrlich P. Cross-coupling of the NF-kB p65 and Fos/Jun transcription factors produces potentiated biological function. EMBO J. 12:3879–3891, 1993.
  • Greene WC. AIDS and the immune system. Sci. Amer. Sept:98–105, 1993.
  • Merida I, Williamson P, Kuziel WA, Greene WC, Gaulton GN. The serine-rich cytoplasmic domain of the interleukin-2 receptor b chain is essential for interleukin-2-dependent tyrosine protein kinase and phosphatidyl-3-kinase activation. J. Biol. Chem. 268:6765–6770, 1993.
  • Sun S-c, Ganchi PA, Ballard DW, Greene WC. NF-kB controls expression of inhibitor IkBa: evidence for an inducible autoregulatory pathway. Science 259:1912–1915, 1993.
  • Bogerd H, Greene WC. Dominant negative mutants of HTLV-I Rex and HIV-1 Rev fail to multimerize in vivo. J. Virol. 67:2496–2502, 1993.
  • Greene WC, Sun S-c, Ganchi P, Doerre S, Ballard DW. The NF-kB/IkB connection: A novel strategy for transcriptional control. In: Saito H, Nariuchi H, Okada H, Okumura K, Takatsuki K, Yodoi J, Nishida M (Eds.), Molecular Basis of Immune Responses, The Proceedings of the First Green Cross International Symposium, Academic Press, 1993, pp. 73–87.
  • Doerre S, Sista P, Ballard DW, Greene WC. The c-rel proto-oncogene product represses NF-kB p65-mediated transcriptional activation of the HIV-1 long terminal repeat. Proc. Natl. Acad. Sci. USA 90:1023–1027, 1993.
  • Hammes SR, Greene WC. Multiple arginine residues within the basic domain of HTLV-I Rex are required for specific RNA binding and function. Virology 193:41–49, 1993.
  • Kuziel WA, Ju G, Grdino TA, Greene WC. Unexpected effects of the IL-2 receptor a subunit on high affinity IL-2 receptor assemble and function detected with a mutant IL-2 analog. J. Immunol. 150:3357–3365, 1993.
  • Greene WC. The molecular biology of HIV-1 and AIDS. In: Sande MA, Root RK (Eds.), Contemporary Issues in Infectious Diseases, Vol. 10, Churchill Livingstone Publishers, New York, 1993, pp. 161–179.
  • Mills GB, Arima N, May C, Hill M, Schmandt R, Li J, Miyamoto NG, Greene WC. Neither the LCK nor the FYN kinases are obligatory for the IL-2-mediated signal transduction in HTLV-I-infected human T cells. International Immunol. 4:1233–43, 1992.
  • Ganchi PA, Sun S-c, Greene WC, Ballard DW. IkB/MAD-3 masks the nuclear localization signal of NF-kB p65 and requires the transactivation domain to inhibit NF-kB p65 DNA binding. Mol. Biol. Cell 3:1339–1352, 1992.
  • Weichselbraun I, Berger J, Dobrovnik M, Bogerd H, Grassman R, Greene WC, Hauber J, Bshnlein E. Dominant-negative mutants are clustered in a domain of the human T-cell leukemia type I Rex protein: Implications for transdominance. J. Virol. 66:4540–4545, 1992.
  • Walker WH, Stein B, Ganchi PA, Hoffman JA, Kaufman PA, Ballard DW, Hannink M, Greene WC. The v-Rel oncogene: Insights into the mechanism of transcriptional activation, repression, and transformation. J. Virol. 66:5018–5029, 1992.
  • Feinberg MB, Greene WC. Molecular insights into HIV-1 pathogenesis. Cur. Opin. Immunol. 4:466–474, 1992.
  • Arima N, Kuziel WA, Grdina TA, Greene WC. Interleukin-2-induced signal transduction involves the activation of nuclear NF-kB expression. J. Immunol. 149:83–91, 1992.
  • Kaufman PA, Weinberg JB, Greene WC. Nuclear expression of the 50- and 65-kD rel-related subunits of nuclear factor-kB is differentially regulated in human monocytic cells. J. Clin. Invest. 90:121–129, 1992.
  • Schmandt R, Fung M, Arima N, Zhang N, Leung B, May C, Gibson S, Hill M, Greene WC, Mills GB. T-lymphocyte proliferation: Tyrosine kinases in interleukin 2 signal transduction. In: Bolliere's Clinical Hematology, Vol.Ê 5, 1992, pp. 551–573.
  • Greene WC. The interleukins. In: Gallin J, Goldstein I, Snyderman R (Eds.), Inflammation: Basic Principles and Clinical Correlations, Raven Press, New York, 1992, pp. 233–246.
  • Ballard DW, Dixon EP, Peffer NJ, Bogerd H, Doerre S, Greene WC. The 65-kDa subunit of human NF-kB functions as a potent transcriptional activator and a target for v-Rel mediated repression. Proc. Natl. Acad. Sci. USA 89:1875–1879, 1992.
  • Kelly K, Davis P, Mitsuya H, Irving S, Wright J, Grassman R, Fleckenstein B, Wano Y, Greene WC, Siebenlist U. A high proportion of early response genes are constitutively activated in T cells by HTLV-I X region-encoded products. Oncogene 7:1463–1470, 1992.
  • Smith MR, Greene WC. Characterization of a novel nuclear localization signal in the HTLV-1 tax transactivator protein. Virology 187:316–320, 1992.
  • Arima N, Molitor JA, Smith MR, Kim JH, Daitoku Y, Greene WC. Human T-cell leukemia virus type I tax induces expression of the Rel-related family of kB enhancer-binding proteins: evidence for a pretranslational component of regulation. J. Virol. 65:6892–6899, 1991.
  • Smith MR, Greene WC. Functional analyses of the type I human T-cell leukemia virus tax gene product. In: Transactions of the Association of American Physicians, Waverly Press, Maryland, 1991, pp. 78–91.
  • Molitor JA, Ballard DW, Greene WC. kB-specific DNA binding proteins are differentially inhibited by enhancer mutations and biological oxidation. The New Biologist 3:987–996, 1991.
  • Smith MR, Greene WC. The HTLV-I tax protein transforms rat fibroblasts through the CREB/ATF pathway. J. Clin. Inves. 88:1038–1042, 1991.
  • Fung MR, Scearce RM, Hoffman JA, Peffer NJ, Hammes SR, Hosking JB, Schmandt R, Kuziel WA, Haynes BF, Mills GB, Greene WC. A tyrosine kinase physically associates with the b-subunit of the human IL-2 receptor. J. Immunol. 147:1253–1260, 1991.
  • Bogerd HP, Huckaby GL, Ahmed AF, Hanly SM, Greene WC. The HTLV-I rex trans-activator binds directly to the HTLV-I Rex and HIV-1 Rev RNA Response Elements. Proc. Natl. Acad. Sci. USA 88:5704–5708, 1991.
  • Hemar A, Cereghini S, Cornet V, Blank V, Israel A, Greene WC, Dautry-Varsat A. kB binding proteins are constitutively expressed in an IL-2 autocrine human T cell line. J. Immunol. 146:2409–2416, 1991.
  • Mills GB, Zhang N, Schmandt R, Fung M, Greene WC, Mellor A, Hogg D. Transmembrane signalling by interleukin-2. Biochem. Transactions 19:277–287, 1991.
  • Smith MR, Greene WC. Molecular biology of HTLV-I and the adult T-cell leukemia. J. Clin. Invest. 87:761–766, 1991.
  • Lee JH, Li Y, Doerre S, Sista P, Ballard DW, Greene WC, Franza Jr. BR. A member of the set of NF-kB binding proteins, HIVEN86A, is a product of the human c-rel proto-oncogene. Oncogene Ê6:665–667, 1991.
  • Ballard DW, Walker WH, Doerre S, Sista P, Molitor JA, Hannink M, Greene WC. Identification of a Rel related family of kB enhancer binding proteins: implications for the regulation of HIV-1 gene expression. In: Haseltine WA, Wong-Staal F (Eds.), The Structure and Regulation of HIV, Raven Press, New York, 1991, pp. 405–414.
  • Ahmed YF, Gilmartin GM, Nevins JR, Greene WC. The HTLV-I Rex response element mediates a novel form of mRNA polyadenylation. Cell 64:727–737, 1991.
  • Greene WC. The molecular biology of HIV-1 infection. New Eng. J. Med. 324:308–317, 1991.
  • Kim JH, Hanly SM, Rimsky LT, Greene WC. Rex transregulation of human T-cell leukemia virus type II gene expression. J. Virol. 65:405–414, 1991.
  • Greene WC. Human interleukin-2 receptors. In: Roitt IM, Delves PJ (Eds.), Encyclopedia of Immunology, W.B. Saunders, 1991.
  • Kuziel WA, Greene WC. Interleukin-2. In: Thomson AW (Ed.), The Cytokine Handbook, Academic Press, Ltd., London, UK, 1991, pp. 83–102.

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