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Supporting Gladstone
Publications 2000-2003
  • Zander K, Sherman MP, Tessmer U, Bruns K, Wray V, Prechtel AT, Schubert E, Henklein P, Luban J, Neidleman J, Greene WC, Schubert U. Cyclophilin A interacts with HIV-1 and is required for its functional expression. J. Biol. Chem. 44:43202–43213, 2003.
  • Chen L-f, Greene WC. Regulation of distinct biological activities of the NF-kB transcription factor complex by acetylation. J. Mol. Med. 81:549–557, 2003.
  • Stopak K, de Noronha C, Yonemoto W, Greene WC. HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability. Mol. Cell.12:591–601, 2003.
  • Sherman MP, de Noronha CMC, Eckstein LA, Hataye J, Mundt P, Williams SAF, Neidleman JA, Goldsmith MA, Greene WC. Nuclear export of Vpr is required for efficient replication of human immunodeficiency virus type 1 in tissue macrophages. J. Virol. 77:7582–7589, 2003.
  • O'Mahony A, Chen L-f, Greene WC. New insights into the regulation of NF-kB: Roles for phosphorylation and acetylation of NF-kB subunits. In: Nuclear Factor kB: Regulation and Role in Disease (Beyaert R, ed.) Kluwer Academic Publishers, Netherlands, pp161–178. In Press.
  • Stoddart CA, Geleziunas R, Ferrell S, Linquist-Stepps V, Moreno ME, Bare C, Xu W, Yonemoto W, Bresnahan PA, McCune JM, Greene WC. Human immunodeficiency virus type 1 nef-mediated downregulation of CD4 correlates with nef enhancement of viral pathogenesis J. Virol. 77:2124–2133, 2003.
  • Chen L-f, Mu Y, Greene WC. Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kB. EMBO J. 21:6539–6548, 2002.
  • Cavrois M, de Noronha C, Greene WC. A sensitive and specific enzyme-based assay detecting HIV-1 virion fusion in primary T lymphocytes. Nat. Biotechnol., 20:1151–1154, 2002.
  • Sherman MP, de Noronha C, Williams SA, Greene WC. Insights into the biology of HIV-1 viral protein R. DNA Cell Biol., 21:679–688, 2002.
  • Greene WC, Peterlin BM. Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy. Nat. Med. 8:673–680, 2002.
  • Sherman MP, Greene WC. Slipping through the door: HIV entry into the nucleus. Review in: Microbes and Infection 4:67–73, 2002.
  • Sherman MP, Schubert U, Williams SA, de Noronha C, Kreisberg JF, Henklein P, Greene WC. HIV Vpr displays natural protein transducing properties: Implications for viral pathogenesis. Virology, 302:95–105, 2002.
  • Eckstein DA, Sherman MP, Penn ML, Chin PS, de Noronha C, Greene WC, Goldsmith MA. HIV-1 Vpr enhances viral burden by facilitating infection of tissue macrophages but not nondividing CD4+ T cells. J. Exp. Med. 194:1407–1419, 2001.
  • de Noronha C, Sherman MP, Lin HW, Cavrois M, Moir RD, Goldman RD, Greene WC. Dynamic disruptions in nuclear envelope architecture and integrity induced by HIV-1 Vpr. Science 294:1105–1108, 2001.
  • Chen L-f, Fischle W, Verdin E, Greene WC. Duration of nuclear NF-kB action regulated by reversible acetylation. Science 293:1653–1657, 2001.
  • Geleziunas R, Xu W, Takeda K, Ichijo H, Greene WC. HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell. Nature 410:834–838, 2001.
  • Sherman MP, de Noronha C, Heusch MI, Greene S, Greene WC. Nucleocytoplasmic shuttling by the human immunodeficiency virus type 1 Vpr. J. Virol. 75:1522–1532, 2001.
  • Schaeffer E, Geleziunas R, Greene WC. Human immunodeficiency virus type 1 Nef functions at the level of virus entry by enhancing cytoplasmic delivery of virions. J. Virol. 75:2993–3000, 2001.
  • Foehr ED, Bohuslav J, Chen L-f, deNoronha C, Geleziunas R, Lin X, O'Mahony A, Greene WC. The NF-kB-inducing kinase NIK induces PC12 cell differentiation and prevents apoptosis. J. Biol. Chem. 275:34021–34024, 2000.
  • Foehr ED, Lin X, O'Mahony A, Geleziunas R, Bradshaw RA, Greene WC. NF-kB signaling promotes both cell survival and neurite process formation in nerve growth factor stimulated PC12 cells. J. Neuroscience 20:7556–7563, 2000.
  • Lin L, DeMartino GN, Greene WC. Cotranslational dimerization of the Rel homology domain of NF-kB1 generates p50-p105 heterodimers and is required for effective p50 production. EMBO J. 19:4712–4722, 2000.
  • Henklein P, Bruns K, Sherman MP, Tessmer U, Licha K, Kopp J, de Noronha CMC, Greene WC, Wray V, Schubert U. Functional and structural characterization of synthetic HIV-1 Vpr that transduces cells, localizes to the nucleus, and induces G2 cell cycle arrest. J. Biol. Chem. 275:32016–32026, 2000.
  • Sherman MP, de Noronha C, Pearce D, Greene WC. Human immunodeficiency virus type I Vpr contains two leucine-rich helices that mediate glucocorticoid receptor coactivation independently of its effects on G2 cell cycle arrest. J. Virol. 74:8159–8165, 2000.
  • Lin X, O'Mahony A, Mu Y, Geleziunas R, Greene WC. Protein kinase C-q participates in NF-kB activation induced by CD3-CD28 costimulation through selective activation of IkB kinase b. Mol. Cell. Biol. 20:2933–2940, 2000.
  • O'Mahony A, Lin X, Geleziunas R, Greene WC. Activation of the heterodimeric IkB kinase a (IKKa)-IKKb complex is directional: IKKa regulates IKKb under both basal and stimulated conditions. Mol. Cell. Biol. 20:1170–1178, 2000.

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