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2005

Aiyer AR, Honarpour N, Herz J, Srivastava D (2005) Loss of Apaf-1 leads to partial rescue of the HAND2-null phenotype. Dev. Biol. 278:155–162.

Aslanian AM, Chapman HA, Charo IF (2005) Transient role for CD1d-restricted natural killer T cells in the formation of atherosclerotic lesions. Arterioscler. Thromb. Vasc. Biol. 25: 628–632.

Barker CS, Griffin C, Dolganov GM, Hanspers K, Yang JYH, Erle DJ (2005) Increased DNA microarray hybridization specificity using sscDNA targets. BMC Genomics 6:57.

Bersot TP, Mahley RW (2005) Clinical classifications of lipid abnormalities. In: Atherothrombosis and Coronary Artery Disease, 2nd edition (Fuster V, Topol EJ, Nabel EG, eds) Lippincott Williams & Wilkins, Philadelphia, pp 129–137.

Chang S, Ma T, Miranda RD, Balestra ME, Mahley RW, Huang Y (2005) The lipid- and receptor-binding domains of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and toxicity in neuronal cell cultures. Proc. Natl. Acad. Sci. USA. 102:18694–18699.

Chen HC, Farese RV Jr (2005) Inhibition of triglyceride synthesis as a treatment strategy for obesity: Lessons from DGAT1-deficient mice. Atheroscler. Thromb. Vasc. Biol. 25:482–486.

Costantini DL, Arruda EP, Agarwal P, Kim KH, Zhu Y, Zhu W, Lebel M, Cheng CW, Park CY, Pierce SA, Guerchicoff A, Pollevick GD, Chan TY, Kabir MG, Cheng SH, Husain M, Antzelevitch C, Srivastava D, Gross GJ, Hui CC, Backx PH, Bruneau BG (2005) The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient. Cell 123:347–358.

Garg V, Muth AN, Ransom JF, Schluterman MK, Barnes R, King IN, Grossfeld PD, Srivastava D (2005) Mutations in NOTCH1 cause aortic valve disease. Nature 437:270–274.

Hasty AH, Plummer MR, Weisgraber KH, Linton MF, Fazio S, Swift LL (2005) The recycling of apolipoprotein E in macrophages: Influence of HDL and apolipoprotein AI. J. Lipid Res. 46:1433–1439.

Hatters DM, Budamagunta MS, Voss JC, Weisgraber KH (2005) Modulation of apolipoprotein E structure by domain interaction. Differences in lipid-bound and lipid-free forms. J. Biol. Chem. 280:34288–34295.

Hodoglugil U, Williamson DW, Huang Y, Mahley RW (2005) An interaction between the TaqIB polymorphism of cholesterol ester transfer protein and smoking is associated with changes in plasma high-density lipoprotein cholesterol levels in Turks. Clin. Genet. 68:118–127.

Hodoglugil U, Williamson DW, Huang Y, Mahley RW (2005) Common polymorphisms of ATP binding cassette transporter A1, including a functional promoter polymorphism, associated with plasma high density lipoprotein cholesterol levels in Turks. Atherosclerosis 183:199–212.

Huang D, Wujek J, Kidd G, He TT, Cardona A, Sasse ME, Stein EJ, Kish J, Tani M, Charo IF, Proudfoot AE, Rollins BJ, Handel T, Ransohoff RM (2005) Chronic expression of monocyte chemoattractant protein-1 in the central nervous system causes delayed encephalopathy and impaired microglial function in mice. FASEB J. 19:761–772.

Kasravi FB, Lee DH, Weisgraber K, Harris HW (2005) Lipoprotein-bound endotoxin exerts an immunomodulatory effect on hepatocytes through the lipid A domain of LPS. J. Endotoxin Res. 11:19–24.

Kwon C, Han Z, Olson EN, Srivastava D (2005) MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling. Proc. Natl. Acad. Sci. USA 102:18986–18991.

Mahley RW, Can S, Özbayrakç? S, Bersot TP, Tanir S, Palaoglu KE, Pépin GM (2005) Modulation of high-density lipoproteins in a population in Istanbul, Turkey, with low levels of high-density lipoproteins. Am. J. Cardiol. 96:547–555.

Mahley RW, Palaoglu KE (2005) What is the “normal” cholesterol in Turks? Türkiye Klinikleri J. Int. Med. Sci. 1:26–32.

McCloskey DT, Turnbull L, Swigart PM, Zambon AC, Turcato S, Joho S, Grossman W, Conklin BR, Simpson PC, Baker AJ (2005) Cardiac transgenesis with the tetracycline transactivator changes myocardial function and gene expression. Physiol. Genomics 22:118–126.

McFadden DG, Barbosa AC, Richardson JA, Schneider MD, Srivastava D, Olson EN (2005) The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner. Development 132:189-201.

Newhouse Y, Peters-Libeu C, Weisgraber KH (2005) Crystallization and preliminary x-ray diffraction analysis of apolipoprotein E-containing lipoprotein particles. Acta Crystallogr. F 61:981–984.

Raffai RL, Loeb SM, Weisgraber KH (2005) Apolipoprotein E promotes atherosclerosis regression independently of lowering plasma cholesterol levels. Arterioscler. Thromb. Vasc. Biol. 25:436–441.

Ruiz J, Kouiavskaia D, Migliorini M, Robinson S, Saenko EL, Gorlatova N, Li D, Lawrence D, Hyman BT, Weisgraber KH, Strickland DK (2005) The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor. J. Lipid Res. 46:1721–1731.

Salomonis NG, Cotte N, Zambon AC, Pollard KS, Vranizan K, Doniger SW, Dolganov G, Conklin BR (2005) Identifying genetic networks underlying myometrial transition to labor. Genome Biol. 6:R12.

Sauer I, Dunay IR, Weisgraber K, Bienert M, Dathe M (2005) An apolipoprotein E-derived peptide mediates uptake of sterically stabilized liposomes into brain capillary endothelial cells. Biochemistry 44:2021–2029.

Scearce-Levie K, Lieberman MD, Elliott HH, Conklin BR (2005) Engineered G protein coupled receptors reveal independent regulation of internalization, desensitization and acute signaling. BMC Biol. 3:3.

Schneider M, Witztum JL, Young SG, Ludwig EH, Miller ER, Tsimikas S, Curtiss LK, Marcovina SM, Taylor JM, Lawn RM, Innerarity TL, Pitas RE (2005) High-level lipoprotein [a] expression in transgenic mice: Evidence for oxidized phospholipids in lipoprotein [a] but not in low density lipoproteins. J. Lipid Res. 46:769–778.

Veillard NR, Steffens S, Pelli G, Lu B, Kwak BR, Gerard C, Charo IF, Mach F (2005) Differential influence of chemokine receptors CCR2 and CXCR3 in development of atherosclerosis in vivo. Circulation 112:870–878.

Wyszynski DF, Waterworth DM, Barter PJ, Cohen J, Kesäniemi YA, Mahley RW, McPherson R, Waeber G, Bersot TP, Sharma SS, Nolan V, Middleton LT, Sundseth SS, Farrer LA, Mooser V, Grundy SM (2005) Relation between atherogenic dyslipidemia and the Adult Treatment Program-III definition of metabolic syndrome (Genetic Epidemiology of Metabolic Syndrome Project). Am. J. Cardiol. 95:194–198.

Yen CL, Brown CHt, Monetti M, Farese RV Jr (2005) A human skin multifunctional O-acyltransferase that catalyzes the synthesis of acylglycerols, waxes, and retinyl esters. J. Lipid Res. 46:2388–2397.

Yen CL, Monetti M, Burri BJ, Farese RV Jr (2005) The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters. J. Lipid Res. 46:1502–1511.

Yu Y, Wyszynski DF, Waterworth DM, Wilton SD, Barter PJ, Kesaniemi YA, Mahley RW, McPherson R, Waeber G, Bersot TP, Ma Q, Sharma SS, Montgomery DS, Middleton LT, Sundseth SS, Mooser V, Grundy SM, Farrer LA (2005) Multiple QTLs influencing triglyceride and HDL and total cholesterol levels identified in families with atherogenic dyslipidemia. J. Lipid Res. 46:2202–2213.

Zambon AC, Zhang L, Minovitsky S, Kanter JR, Prabhakar S, Salomonis N, Vranizan K, Dubchak I, Conklin BR, Insel PA (2005) Gene expression patterns define key transcriptional events in cell-cycle regulation by cAMP and protein kinase A. Proc. Natl. Acad. Sci. USA 102:8561–8566.

Zhang S, Picard MH, Vasile E, Zhu Y, Raffai RL, Weisgraber KH, Krieger M (2005) Diet-induced occlusive coronary atherosclerosis, myocardial infarction, cardiac dysfunction, and premature death in scavenger receptor class B type I-deficient, hypomorphic apolipoprotein ER61 mice. Circulation 111:3457–3464.

Zhao Y, Samal E, Srivastava D (2005) Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature 436:214–220.

Zhao Y, Thorngate FE, Weisgraber KH, Williams DL, Parks JS (2005) Apolipoprotein E is the major physiological activator of lecithin–cholesterol acyltransferase (LCAT) on apolipoprotein B lipoproteins. Biochemistry 44:1013–1025.


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