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2001

Baker AJ, Redfern CH, Harwood MD, Simpson PC, Conklin BR (2001) Abnormal contraction caused by expression of Gi-coupled receptor in transgenic model of dilated cardiomyopathy. Am. J. Physiol. 280:H1653–H1659.

Belperio JA, Keane MP, Burdick MD, Lynch III JP, Xue YY, Berlin A, Ross DJ, Kunkel SL, Charo IF, Strieter RM (2001) Critical role for the chemokine MCP-1/CCR2 in the pathogenesis of bronchiolitis obliterans syndrome. J. Clin. Invest. 108:547–556.

Bergo MO, Leung GK, Ambroziak P, Otto JC, Casey PJ, Gomes AQ, Seabra MC, Young SG (2001) Isoprenylcysteine carboxyl methyltransferase deficiency in mice. J. Biol. Chem. 276:5841–5845.

Björkegren J, Véniant M, Kim SK, Withycombe SK, Wood PA, Hellerstein MK, Neese RA, Young SG (2001) Lipoprotein secretion and triglyceride stores in the heart. J. Biol. Chem. 276:38511–38517.

Borén J, Ekström U, Ågren B, Nilsson-Ehle P, Innerarity TL (2001) The molecular mechanism for the genetic disorder familial defective apolipoprotein B100. J. Biol. Chem. 276:9214–9218.

Buhman KK, Chen HC, Farese RV Jr (2001) The enzymes of neutral lipid synthesis. J. Biol. Chem. 276:40369–40372.

Cases S, Stone SJ, Zhou P, Yen E, Tow B, Lardizabal KD, Voelker T, Farese RV Jr (2001) Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members. J. Biol. Chem. 276:38870–38876.

Chen HC (2001) Molecular mechanisms of sterol absorption. J. Nutr. 131:2603–2605.

Chen HC (2001) Intravenous calcium replacement for asymptomatic hypocalcemia of chritical illness. The Endocrinologist 11:364–367.

Chen HC, Farese RV Jr (2001) Turning WAT into BAT gets rid of fat. Nat. Med. 7:1102–1103.

DeYoung MB, Tom C, Dichek DA (2001) Plasminogen activator inhibitor type 1 increases neointima formation in balloon-injured rat carotid arteries. Circulation 104:1972–1977.

Dichek HL, Johnson SM, Akeefe H, Lo GT, Sage E, Yap CE, Mahley RW (2001) Hepatic lipase overexpression lowers remnant and LDL levels by a noncatalytic mechanism in LDL receptor-deficient mice. J. Lipid Res. 42:201–210.

Dong J, Peters-Libeu C, Weisgraber KH, Segelke BW, Rupp B, Capila I, Hernáiz MJ, LeBrun LA, Linhardt RJ (2001) Interaction of the N-terminal domain of apolipoprotein E4 with heparin. Biochemistry 40:2826–2834.

Drake PM, Gunn MD, Charo IF, Tsou C-L, Zhou Y, Huang L, Fisher SJ (2001) Human placental cytotrophoblasts attract monocytes and CD56bright natural killer cells via the actions of monocyte inflammatory protein 1a. J. Exp. Med. 193:1199–1212.

Driscoll DM, Innerarity TL (2001) RNA editing by cytidine deamination in mammals. In: RNA Editing (Bass BL, ed) Oxford University Press, Oxford, England, pp 61–76.

Dupuis M, Denis-Mize K, LaBarbara A, Peters W, Charo IF, McDonald DM, Ott G (2001) Immunization with the adjuvant MF59 induces macrophage trafficking and apoptosis. Eur. J. Immunol. 31:2910–2918.

Fazio S, Major AS, Swift LL, Gleaves LA, Accad M, Linton MF, Farese RV Jr (2001) Increased atherosclerosis in LDL receptor–null mice lacking ACAT1 in macrophages. J. Clin. Invest. 107:163–171.

Grehan S, Allan C, Tse E, Walker D, Taylor JM (2001) Expression of the apolipoprotein E gene in the skin is controlled by a unique downstream enhancer. J. Invest. Dermatol. 116:77–84.

Grehan S, Tse E, Taylor JM (2001) Two distal downstream enhancers direct expression of the human apolipoprotein E gene to astrocytes in the brain. J. Neurosci. 21:812–822.

Haskell CA, Hancock WW, Salant DJ, Gao W, Csizmadia V, Peters W, Faia K, Fituri O, Rottman JB, Charo IF (2001) Targeted deletion of CX3CR1 reveals a role for fractalkine in cardiac allograft rejection. J. Clin. Invest. 108:679–688.

Hersberger M, Santiago-Garcia J, Patarroyo-White S, Yan J, Xu X (2001) A dinucleotide deletion in amyloid precursor protein (APP) mRNA associated with sporadic Alzheimer’s disease results in efficient secretion of truncated APP isoforms from neuroblastoma cell cultures. J. Neurochem. 76:1308–1314.

Huang Y, Liu XQ, Wyss-Coray T, Brecht WJ, Sanan DA, Mahley RW (2001) Apolipoprotein E fragments present in Alzheimer’s disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons. Proc. Natl. Acad. Sci. USA 98:8838–8843.

Leung GK, Schmidt WK, Bergo MO, Gavino B, Wong DH, Tam A, Ashby MN, Michaelis S, Young SG (2001) Biochemical studies of Zmpste24-deficient mice. J. Biol. Chem. 276:29051–29058.

Libeu CP, Lund-Katz S, Phillips MC, Wehrli S, Hernáiz MJ, Capila I, Linhardt RJ, Raffaï RL, Newhouse YM, Zhou F, Weisgraber KH (2001) New insights into the heparan sulfate proteoglycan-binding activity of apolipoprotein E. J. Biol. Chem. 276:39138–39144.

Lowenson JD, Kim E, Young SG, Clarke S (2001) Limited accumulation of damaged proteins in L-isoaspartyl (D-aspartyl) O-methyltransferase-deficient mice. J. Biol. Chem. 276:20695–20702.

Lund-Katz S, Wehrli S, Zaiou M, Newhouse Y, Weisgraber KH, Phillips MC (2001) Effects of polymorphism on the microenvironment of the LDL receptor-binding region of human apoE. J. Lipid Res. 42:894–901.

Mahley RW (2001) Biochemistry and physiology of lipid and lipoprotein metabolism. In: Principles and Practice of Endocrinology and Metabolism, 3rd edition (Becker KL, eds) Lippincott Williams & Wilkins, Philadelphia, pp 1503–1513.

Mahley RW, Arslan P, Pekcan G, Pépin GM, Agaçdiken A, Karaagaoglu N, Rakicioglu N, Nursal B, Dayanikli P, Palaoglu KE, Bersot TP (2001) Plasma lipids in Turkish children: Impact of puberty, socioeconomic status, and nutrition on plasma cholesterol and HDL. J. Lipid Res. 42:1996–2006.

Mahley RW, Bersot TP (2001) Drug therapy for hypercholesterolemia and dyslipidemia. In: Goodman & Gilman’s The Pharmacological Basis of Therapeutics, 10th edition (Hardman JG, Limbird LE, Gilman AG, eds) McGraw-Hill, New York, pp 971–1002.

Mahley RW, Bersot TP (2001) Statins: Overwhelming evidence of efficacy and safety of these hypolipidemic drugs. Turk. J. Endocrinol. Metab. 5:131–140.

Mahley RW, Rall SC Jr (2001) Type III hyperlipoproteinemia (dysbetalipoproteinemia): The role of apolipoprotein E in normal and abnormal lipoprotein metabolism. In: The Metabolic and Molecular Bases of Inherited Disease, 8th edition (Scriver CR, Beaudet AL, Sly WS, Valle D, Childs B, Kinzler KW, Vogelstein B, eds) McGraw-Hill, New York, pp 2835–2862.

Peters W, Charo IF (2001) Involvement of chemokine receptor 2 and its ligand, monocyte chemoattractant protein-1, in the development of atherosclerosis: Lessons from knockout mice. Curr. Opin. Lipidol. 12:175–180.

Peters W, Scott HM, Chambers HF, Flynn JL, Charo IF, Ernst JD (2001) Chemokine receptor 2 serves an early and essential role in resistance to Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. USA 98:7958–7963.

Raffaï RL, Dong L-M, Farese RV Jr, Weisgraber KH (2001) Introduction of human apolipoprotein E4 “domain interaction” into mouse apolipoprotein E. Proc. Natl. Acad. Sci. USA 98:11587–11591.

Saito H, Dhanasekaran P, Baldwin F, Weisgraber KH, Lund-Katz S, Phillips MC (2001) Lipid binding-induced conformational change in human apolipoprotein E. Evidence for two lipid-bound states on spherical particles. J. Biol. Chem. 276:40949–40954.

Santiago-García J, Mas-Oliva J, Innerarity TL, Pitas RE (2001) Secreted forms of the amyloid-b precursor protein are ligands for the class A scavenger receptor. J. Biol. Chem. 276:30655–30661.

Scearce-Levie K, Coward P, Redfern CH, Conklin BR (2001) Engineering receptors activated solely by synthetic ligands (RASSLs). Trends Pharmacol. Sci. 22:414–420.

Sonda S, Ting L-M, Novak S, Kim K, Maher JJ, Farese RV Jr, Ernst JD (2001) Cholesterol esterification by host and parasite is essential for optimal proliferation of Toxoplasma gondii. J. Biol. Chem. 276:34434–34440.

Tsou C-L, Haskell CA, Charo IF (2001) Tumor necrosis factor-a-converting enzyme mediates the inducible cleavage of fractalkine. J. Biol. Chem. 276:44622–44626.

Véniant MM, Withycombe S, Young SG (2001) Lipoprotein size and atherosclerosis susceptibility in Apoe–/– and Ldlr–/– mice. Arterioscler. Thromb. Vasc. Biol. 21:1567–1570.

Wen S, Driscoll RM, Schneider DB, Dichek DA (2001) Inclusion of the E3 region in an adenoviral vector decreases inflammation and neointima formation after arterial gene transfer. Arterioscler. Thromb. Vasc. Biol. 21:1777–1782.

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