Aguilar-Salinas CA, Barrett PHR, Parhofer KG, Young SG, Tessereau D, Bateman J, Quinn C, Schonfeld G (1995) Apoprotein B-100 production is decreased in subjects heterozygous for truncations of apoprotein B. Arterioscler. Thromb. Vasc. Biol. 15:71–80.

Allan CM, Walker D, Segrest JP, Taylor JM (1995) Identification and characterization of a new human gene (APOC4) in the apolipoprotein E, C-I, and C-II gene locus. Genomics 28:291–300.

Allan CM, Walker D, Taylor JM (1995) Evolutionary duplication of a hepatic control region in the human apolipoprotein E gene locus. Identification of a second region that confers high level and liver-specific expression of the human apolipoprotein E gene in transgenic mice. J. Biol. Chem. 270:26278–26281.

Bellosta S, Mahley RW, Sanan DA, Murata J, Newland DL, Taylor JM, Pitas RE (1995) Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E–null mice. J. Clin. Invest. 96:2170–2179.

Bellosta S, Nathan BP, Orth M, Dong L-M, Mahley RW, Pitas RE (1995) Stable expression and secretion of apolipoproteins E3 and E4 in mouse neuroblastoma cells produces differential effects on neurite outgrowth. J. Biol. Chem. 270:27063–27071.

Boylan AM, Sanan DA, Sheppard D, Broaddus VC (1995) Vitronectin enhances internalization of crocidolite asbestos by rabbit pleural mesothelial cells via the integrin avb5. J. Clin. Invest. 96:1987–2001.

Bucala R, Mitchell R, Arnold K, Innerarity T, Vlassara H, Cerami A (1995) Identification of the major site of apolipoprotein B modification by advanced glycosylation end products blocking uptake by the low density lipoprotein receptor. J. Biol. Chem. 270:10828–10832.

Chambers M, Weisman S, Li CQ, López JA (1995) Mapping of mAb to CD42a and CD42b and of unassigned mAb in transfected cell lines expressing the gpIb/IX complex. In: Leucocyte Typing V (Schlossman SF, Boumsell L, Gilks W, Harlan JM, Kishimoto T, Morimoto C, Ritz J, Shaw S, Silverstein R, Springer T, Tedder TF, Todd RF, eds) Oxford University Press, Oxford, England, pp 1343–1345.

Dang Q, Walker D, Taylor S, Allan C, Chin P, Fan J, Taylor J (1995) Structure of the hepatic control region of the human apolipoprotein E/C-I gene locus. J. Biol. Chem. 270:22577–22585.

Davidson NO, Innerarity TL, Scott J, Smith H, Driscoll DM, Teng B, Chan L (1995) Proposed nomenclature for the catalytic subunit of the mammalian apolipoprotein B mRNA editing enzyme: APOBEC-1. RNA 1:3.

De Pauw M, Vanloo B, Weisgraber K, Rosseneu M (1995) Comparison of lipid-binding and lecithin:cholesterol acyltransferase activation of the amino- and carboxyl-terminal domains of human apolipoprotein E3. Biochemistry 34:10953–10960.

Dong J-F, Hyun W, López JA (1995) Aggregation of mammalian cells expressing the platelet glycoprotein (GP) Ib-IX complex and the requirement for tyrosine sulfation of GP Iba. Blood 86:4175–4183.

Evans KC, Berger EP, Cho C-G, Weisgraber KH, Lansbury PT Jr (1995) Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: Implications for the pathogenesis and treatment of Alzheimer disease. Proc. Natl. Acad. Sci. USA 92:763–767.

Fan J, Mahley RW, Taylor JM (1995) Transgenic rabbits that overexpress hepatic lipase have a marked reduction of plasma high density lipoproteins and intermediate density lipoproteins. In: Atherosclerosis X (Woodford FP, Davignon J, Sniderman A, eds) Elsevier Science, Amsterdam, pp 666–669.

Fan J, McCormick SPA, Krauss RM, Taylor S, Quan R, Taylor JM, Young SG (1995) Overexpression of human apolipoprotein B-100 in transgenic rabbits results in increased levels of LDL and decreased levels of HDL. Arterioscler. Thromb. Vasc. Biol. 15:1889–1899.

Farese RV Jr, Ruland SL, Flynn LM, Stokowski RP, Young SG (1995) Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes. Proc. Natl. Acad. Sci. USA 92:1774–1778.

Fazio S, Yao Z (1995) The enhanced association of apolipoprotein E with apolipoprotein B–containing lipoproteins in serum-stimulated hepatocytes occurs intracellularly. Arterioscler. Thromb. Vasc. Biol. 15:593–600.

Fox JEB (1995) The interaction of the cytoskeleton with adhesive receptors: Effects on cell adhesion. In: Principles of Cell Adhesion (Richardson PD, Steiner M, eds) CRC Press, Boca Raton, FL, pp 253–268.

Franci C, Wong LM, van Damme J, Proost P, Charo IF (1995) Monocyte chemoattractant protein-3, but not monocyte chemoattractant protein-2, is a functional ligand of the human monocyte chemoattractant protein-1 receptor. J. Immunol. 154:6511–6517.

Gong Q, Pitas RE (1995) Synergistic effects of growth factors on the regulation of smooth muscle cell scavenger receptor activity. J. Biol. Chem. 270:21672–21678.

Grass DS, Saini U, Felkner RH, Wallace RE, Lago WJP, Young SG, Swanson ME (1995) Transgenic mice expressing both human apolipoprotein B and human CETP have a lipoprotein cholesterol distribution similar to that of normolipidemic humans. J. Lipid Res. 36:1082–1091.

Holtzman DM, Pitas RE, Kilbridge J, Nathan B, Mahley RW, Bu G, Schwartz AL (1995) Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line. Proc. Natl. Acad. Sci. USA 92:9480–9484.

Huang DY, Weisgraber KH, Goedert M, Saunders AM, Roses AD, Strittmatter WJ (1995) ApoE3 binding to tau tandem repeat I is abolished by tau serine₂₆₂ phosphorylation. Neurosci. Lett. 192:209–212.

Huang DY, Weisgraber KH, Strittmatter WJ, Matthew WD (1995) Interaction of apolipoprotein E with laminin increases neuronal adhesion and alters neurite morphology. Exp. Neurol. 136:251–257.

Hussain MM, Innerarity TL, Brecht WJ, Mahley RW (1995) Chylomicron metabolism in normal, cholesterol-fed, and Watanabe heritable hyperlipidemic rabbits. Saturation of the sequestration step of the remnant clearance pathway. J. Biol. Chem. 270:8578–8587.

Innerarity TL (1995) Plasma lipoproteins. In: Molecular Biology and Biotechnology. A Comprehensive Desk Reference (Meyers RA, ed) VCH Publishers, New York, pp 703–709.

Ji Z-S, Sanan DA, Mahley RW (1995) Intravenous heparinase inhibits remnant lipoprotein clearance from the plasma and uptake by the liver: In vivo role of heparan sulfate proteoglycans. J. Lipid Res. 36:583–592.

Jo D-W, Leren TP, Yang Z-Y, Chung Y-H, Taylor JM, Paik Y-K (1995) Characterization of an upstream regulatory element of the human apolipoprotein E gene, and purification of its binding protein from the human placenta. J. Biochem. 117:915–922.

Lee SW, Dichek DA (1995) Molecular approaches to the therapy of ischemic heart disease and myocardial infarction. In: Molecular Interventions and Local Drug Delivery (Edelman ER, ed) WB Saunders, London, pp 171–201.

Li CQ, Dong J-F, Lanza F, Sanan DA, Sae-Tung G, López JA (1995) Expression of platelet glycoprotein (GP) V in heterologous cells and evidence for its association with GP Iba in forming a GP Ib-IX-V complex on the cell surface. J. Biol. Chem. 270:16302–16307.

Liu J, Conklin BR, Blin N, Yun J, Wess J (1995) Identification of a receptor/G-protein contact site critical for signaling specificity and G-protein activation. Proc. Natl. Acad. Sci. USA 92:11642–11646.

López JA, Li CQ, Chambers M, Weisman S (1995) The CD42 mAb Sz.1, which blocks a site on the gpIb/IX complex recognized by drug-dependent antibodies, binds a conformation-dependent epitope on gpIX. In: Leucocyte Typing V (Schlossman SF, Boumsell L, Gilks W, Harlan JM, Kishimoto T, Morimoto C, Ritz J, Shaw S, Silverstein R, Springer T, Tedder TF, Todd RF, eds) Oxford University Press, Oxford, England, pp 1341–1343.

López JA, Li CQ, Weisman S, Chambers M (1995) The glycoprotein Ib-IX complex-specific monoclonal antibody SZ1 binds to a conformation-sensitive epitope on glycoprotein IX: Implications for the target antigen of quinine/quinidine-dependent autoantibodies. Blood 85:1254–1258.

Mahley RW (1995) Apolipoprotein E and Alzheimer’s disease. In: HDL Deficiency and Atherosclerosis (Assmann G, ed) Kluwer Academic Publishers, Dordrecht, The Netherlands, pp 53–59.

Mahley RW (1995) Biochemistry and physiology of lipid and lipoprotein metabolism. In: Principles and Practice of Endocrinology and Metabolism, Second edition (Becker KL, ed) JB Lippincott, Philadelphia, pp 1369–1378.

Mahley RW, Ji Z-S (1995) Apolipoprotein E in remnant lipoprotein metabolism: Role of cell-surface heparan sulfate proteoglycans in enhanced hepatic binding and uptake. In: Atherosclerosis X (Woodford FP, Davignon J, Sniderman A, eds) Elsevier Science, Amsterdam, pp 645–650.

Mahley RW, Nathan BP, Bellosta S, Pitas RE (1995) Apolipoprotein E: Impact of cytoskeletal stability in neurons and the relationship to Alzheimer’s disease. Curr. Opin. Lipidol. 6:86–91.

Mahley RW, Palaoglu KE, Atak Z, Dawson-Pepin J, Langlois A-M, Cheung V, Onat H, Fulks P, Mahley LL, Vakar F, Özbayrakçi S, Gökdemir O, Winkler W (1995) Turkish Heart Study: Lipids, lipoproteins, and apolipoproteins. J. Lipid Res. 36:839–859.

Mahley RW, Rall SC Jr (1995) Type III hyperlipoproteinemia (dysbetalipoproteinemia): The role of apolipoprotein E in normal and abnormal lipoprotein metabolism. In: The Metabolic and Molecular Bases of Inherited Disease, 7th edition (Scriver CR, Beaudet AL, Sly WS, Valle D, eds) McGraw-Hill, New York, pp 1953–1980.

Mancini FP, Newland DL, Mooser V, Murata J, Marcovina S, Young SG, Hammer RE, Sanan DA, Hobbs HH (1995) Relative contributions of apolipoprotein(a) and apolipoprotein-B to the development of fatty lesions in the proximal aorta of mice. Arterioscler. Thromb. Vasc. Biol. 15:1911–1916.

McCormick SPA, Day WA, George PM (1995) Characterization of lipoproteins containing a truncated form of apolipoprotein B, apolipoprotein B32. Biochim. Biophys. Acta 1258:49–56.

McCormick SPA, Ng JK, Taylor S, Flynn LM, Hammer RE, Young SG (1995) Mutagenesis of the human apolipoprotein B gene in a yeast artificial chromosome reveals the site of attachment for apolipoprotein(a). Proc. Natl. Acad. Sci. USA 92:10147–10151.

Minnich A, Weisgraber KH, Newhouse Y, Dong L-M, Fortin L-J, Tremblay M, Davignon J (1995) Identification and characterization of a novel apolipoprotein E variant, apolipoprotein E3′ (Arg₁₃₆→His): Association with mild dyslipidemia and double pre-β very low density lipoproteins. J. Lipid Res. 36:57–66.

Myers SJ, Wong LM, Charo IF (1995) Signal transduction and ligand specificity of the human monocyte chemoattractant protein-1 receptor in transfected embryonic kidney cells. J. Biol. Chem. 270:5786–5792.

Nathan BP, Chang K-C, Bellosta S, Brisch E, Ge N, Mahley RW, Pitas RE (1995) The inhibitory effect of apolipoprotein E4 on neurite outgrowth is associated with microtubule depolymerization. J. Biol. Chem. 270:19791–19799.

Newman KD, Dunn PF, Owens JW, Schulick AH, Virmani R, Sukhova G, Libby P, Dichek DA (1995) Adenovirus-mediated gene transfer into normal rabbit arteries results in prolonged vascular cell activation, inflammation, and neointimal hyperplasia. J. Clin. Invest. 96:2955–2965.

Paik Y-K, Reardon CA, Taylor JM, Choi B-K (1995) Characterization of an upstream regulatory sequence and its binding protein in the mouse apolipoprotein E gene. Biochim. Biophys. Acta 1262:124–132.

Palinski W, Tangirala RK, Miller E, Young SG, Witztum JL (1995) Increased autoantibody titers against epitopes of oxidized LDL in LDL receptor–deficient mice with increased atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 15:1569–1576.

Purcell-Huynh DA, Farese RV Jr, Johnson DF, Flynn LM, Pierotti V, Newland DL, Linton MF, Sanan DA, Young SG (1995) Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet. J. Clin. Invest. 95:2246–2257.

Raffaï R, Maurice R, Weisgraber K, Innerarity T, Wang X, MacKenzie R, Hirama T, Watson D, Rassart E, Milne R (1995) Molecular characterization of two monoclonal antibodies specific for the LDL receptor-binding site of human apolipoprotein E. J. Lipid Res. 36:1905–1918.

Roses AD, Saunders AM, Corder EH, Pericak-Vance MA, Han S-H, Einstein G, Hulette C, Schmechel DE, Holsti M, Huang D, Risch NJ, Haines JL, Goedert M, Jakes R, Dong L-M, Weisgraber KH, Strittmatter WJ (1995) Influence of the susceptibility genes apolipoprotein E-e4 and apolipoprotein E-e2 on the rate of disease expressivity of late-onset Alzheimer’s disease. Arzneim.-Forsch./Drug Res. 45:413–417.

Roses AD, Saunders AM, Corder EH, Risch NJ, Haines JL, Pericak-Vance MA, Han S-H, Einstein G, Hulette C, Schmechel DE, Goedert M, Jakes R, Dong L-M, Weisgraber KH, Holsti M, Huang D, Strittmatter WJ (1995) Apolipoprotein E and Alzheimer’s disease. In: Research Advances in Alzheimer’s Disease and Related Disorders (Iqbal K, Mortimer JA, Winblad B, Wisniewski HM, eds) John Wiley & Sons, Chichester, England, pp 85–96.

Rosseneu M, De Pauw M, Vanloo B, Dergunov A, Weisgraber K, Brasseur R (1995) Identification and computer modeling of the functional domains of human apolipoprotein E3. In: Atherosclerosis X (Woodford FP, Davignon J, Sniderman A, eds) Elsevier Science, Amsterdam, pp 651–655.

Saxena U, Auerbach BJ, Ferguson E, Wölle J, Marcel YL, Weisgraber KH, Hegele RA, Bisgaier CL (1995) Apolipoprotein B and E basic amino acid clusters influence low-density lipoprotein association with lipoprotein lipase anchored to the subendothelial matrix. Arterioscler. Thromb. Vasc. Biol. 15:1240–1247.

Schachtner SK, Rome JJ, Hoyt RF Jr, Newman KD, Virmani R, Dichek DA (1995) In vivo adenovirus-mediated gene transfer via the pulmonary artery of rats. Circ. Res. 76:701–709.

Schulick AH, Dong G, Newman KD, Virmani R, Dichek DA (1995) Endothelium-specific in vivo gene transfer. Circ. Res. 77:475–485.

Schulick AH, Newman KD, Virmani R, Dichek DA (1995) In vivo gene transfer into injured carotid arteries. Optimization and evaluation of acute toxicity. Circulation 91:2407–2414.

Weisgraber KH, Pitas RE, Mahley RW (1995) Role of apolipoprotein E in Alzheimer’s disease. In: Atherosclerosis X (Woodford FP, Davignon J, Sniderman A, eds) Elsevier Science, Amsterdam, pp 670–674.

Welty FK, Ordovas J, Schaefer EJ, Wilson PWF, Young SG (1995) Identification and molecular analysis of two apoB gene mutations causing low plasma cholesterol levels. Circulation 92:2036–2040.

Yamanaka S, Balestra ME, Ferrell LD, Fan J, Arnold KS, Taylor S, Taylor JM, Innerarity TL (1995) Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals. Proc. Natl. Acad. Sci. USA 92:8483–8487.

Young SG, Cham CM, Pitas RE, Burri BJ, Connolly A, Flynn L, Pappu AS, Wong JS, Hamilton RL, Farese RV Jr (1995) A genetic model for absent chylomicron formation: Mice producing apolipoprotein B in the liver, but not in the intestine. J. Clin. Invest. 96:2932–2946.

Young SG, McCormick SPA, Purcell-Huynh D, Linton MF, Farese RV Jr (1995) Expression of human apolipoprotein B in transgenic mice. In: Atherosclerosis X (Woodford FP, Davignon J, Sniderman A, eds) Elsevier Science, Amsterdam, pp 377–383.

TOP