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Publications 2007
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Cheng IH, Scearce-Levie K, Legleiter J, Palop JJ, Gerstein H, Bien-Ly N, Puoliväli J, Lesné S, Ashe KH, Muchowski PJ, Mucke L (2007) Accelerating amyloid-β fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models. J. Biol. Chem. 282:23818–23828.
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Chin J, Massaro CM, Palop JJ, Thwin MT, Yu G.-Q, Bien-Ly N, Bender A, Mucke L (2007) Reelin depletion in the entorhinal cortex of human amyloid precursor protein transgenic mice and humans with Alzheimer’s disease. J. Neurosci. 27:2727–2733.
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deIpolyi AR, Rankin K, Mucke L, Miller B, Gorno-Tempini ML (2007) Spatial cognition and the human navigation network in AD and MCI. Neurology 69:986–997.
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Gan L (2007) Therapeutic potential of sirtuin-activating compounds in Alzheimer’s disease. Drug News Perspect. 20:233–239.
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Gan L (2007) The degradation of amyloid-β: Progress toward therapeutic interventions. Fut. Neurol. 2:133–137.
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Gao F.-B (2007) Molecular and cellular mechanisms of dendritic morphogenesis. Curr. Opinion Neurobiol. 17:525–532.
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Lee J.-A, Beigneux A, Ahmad ST, Young SG, Gao F.-B (2007) ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration. Curr. Biol. 17:1561–1567.
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Mahley RW, Bersot TP (2007) High density lipoprotein cholesterol in coronary artery patients: Is it as low as expected? Anatolian J. Cardiol. 6:94–96.
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Mahley RW, Huang Y (2007) Atherogenic remnant lipoproteins: Role for proteoglycans in trapping, transferring, and internalizing. J. Clin. Invest. 117:94–98.
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Palop JJ, Chin J, Roberson ED, Wang J, Thwin MT, Bien-Ly N, Yoo J, Ho KO, Yu G.-Q, Kreitzer A, Finkbeiner S, Noebels JL, Mucke L (2007) Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer’s disease. Neuron 55:695–711.
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Peebles CL, Finkbeiner S (2007) RNA decay back in play. Nat. Med. 10:1083–1084.
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Peters-Libeu CA, Newhouse Y, Hall SC, Witkowska HE, Weisgraber KH (2007) Apolipoprotein E*dipalmitoylphosphatidylcholine particles are ellipsoidal in solution. J. Lipid Res. 48:1035–1044.
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Rao VR, Finkbeiner S (2007) NMDA and AMPA receptors: Old channels, new tricks. Trends Neurosci. 30:284–291.
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Roberson ED, Scearce-Levie K, Palop JJ, Yan F, Cheng I, Wu T, Gerstein H, Yu G.-Q, Mucke L (2007) Reducing endogenous tau ameliorates Aβ-induced deficits in an Alzheimer’s disease mouse model. Science 316:750–754.
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Roses AD, Saunders AM, Huang Y, Strum J, Weisgraber KH, Mahley RW (2007) Complex disease-associated pharmacogenetics: Drug efficacy, drug safety, and confirmation of a pathogenetic hypothesis (Alzheimer’s disease). Pharmacogenomics J. 7:10–28.
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Rosser MF, Wahsburn E, Muchowski PJ, Patterson C, Cyr DM (2007) Chaperone functions of the E3 ubiquitin ligase CHIP. J. Biol Chem. 282:22267–22277.
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Zhang Y, Vasudevan S, Sojitrawala R, Zhao W, Cui C, Xu C, Fan D, Newhouse Y, Balestra R, Jerome WG, Weisgraber K, Li Q, Wang J (2007) A monomeric, biologically active, full-length human apolipoprotein E. Biochemistry 46:10722–10732.
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