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Supporting Gladstone
Selected References
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Palop J, Jones B, Kekonius L, Chin J, Yu G-Q, Raber J, Masliah E, and Mucke L (2003) Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits. Proc. Natl. Acad. Sci. USA 100:9572–9577.[pdf]

Chin J, Palop JJ, Puoliväli J, Massaro C, Bien-Ly N, Gerstein H, Scearce-Levie K, Masliah E, and Mucke L (2005) Fyn kinase induces synaptic and cognitive impairments in a transgenic mouse model of Alzheimer's disease. J. Neurosci. 25:9694–9703.[pdf]

Palop JJ, Chin J, Bien-Ly N, Massaro C, Yeung BZ, Yu G-Q, and Mucke L (2005) Vulnerability of dentate granule cells to disruption of Arc expression in human amyloid precursor protein transgenic mice. J. Neurosci. 25:9686–9693. [pdf]

Palop JJ, Chin J, and Mucke L (2006) A network dysfunction perspective on neurodegenerative diseases. Nature 443:768–773. [pdf]

Roberson ED and Mucke L (2006) 100 years and counting: Prospects for defeating Alzheimer’s disease. Science 314:781–784.[pdf]

Cheng IH, Scearce-Levie K, Legleiter J, Palop JJ, Gerstein H, Bien-Ly N, Puoliväli J, Lesné S, Ashe KH, Muchowski PJ, Mucke L (2007) Accelerating amyloid-β fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models. J. Biol. Chem. 282:23818–23828.[pdf]

Palop JJ, Chin J, Roberson ED, Wang J, Thwin MT, Bien-Ly N, Yoo J, Ho KO, Yu G.-Q, Kreitzer A, Finkbeiner S, Noebels JL, Mucke L (2007) Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer’s disease. Neuron 55:695–711.[pdf]

Roberson ED, Scearce-Levie K, Palop JJ, Yan F, Cheng I, Wu T, Gerstein H, Yu G.-Q, and Mucke L (2007) Reducing endogenous tau ameliorates Aβ-induced deficits in an Alzheimer’s disease mouse model. Science 316:750–754.[pdf]


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