Protein in semen found to boost infectious potential of HIV
By Sabine Russell
The San Francisco Chronicle, December 13, 2007
German AIDS researchers have discovered a protein common in semen that boosts the infectious potential of HIV 100,000-fold—a remarkable finding that may show how the virus can spread through sexual contact and also suggests new strategies to stop the epidemic... MORE
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Japanese scientist Shinya Yamanaka wins top German cancer prize
EUX.TV / The European Affairs Channel, November 26, 2007
Shinya Yamanaka, the Japanese scientist who last week revealed a revolutionary new technique to manufacture stem cells, was chosen Monday as winner of a top German prize for cancer research... MORE
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Breakthrough Could End Debate, Open Up Funding
By Terri Somers
San Diego Union Tribune, November 21, 2007
Scientists have used ordinary skin cells to create the equivalent of human embryonic stem cells, a development that could propel the science above the maelstrom of moral debate and controversy that has choked federal funding... MORE
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Scientist Behind Stem Cell Breakthrough Has Bay Area Ties
KNTV-San Jose NBC-TV, November 20, 2007
A Japanese scientist with research ties to the Bay Area reported Tuesday a breakthrough in stem cell research that has the potential to quell the field's ethical controversies... MORE
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New Stem Cell Method Could Ease Ethical Concerns
By Gina Kolata
The New York Times, November 20, 2007
Two teams of scientists are reporting today that they turned human skin cells into what appear to be embryonic stem cells without having to make or destroy an embryo—a feat that could quell the ethical debate troubling the field... MORE
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Advance in Stem Cells Avoids Ethical Tangles
By Gautam Naik
The Wall Street Journal, November 20, 2007
The promise of using cells from human embryos to treat disease has moved a tantalizing step closer to reality—but without the ethical shackles that have long hindered its progress. The breakthrough is likely to bolster the cause of those who oppose embryo research, and accelerate the pace of stem cell research as scientists rush to build on the new approach... MORE
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Scientists Produce Embryonic Stem Cells from Skin
By Joe Palca
National Public Radio, November 20, 2007
Two teams of scientists have independently discovered a way to turn ordinary human skin cells into stem cells with the same characteristics as those derived from human embryos, a breakthrough that could open the door for advanced medical therapies.... MORE
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Stem Cell Breakthrough Uses No Embryos
By Associated Press
KGO-TV ABC-7 News, November 20, 2007
Scientists have made ordinary human skin cells take on the chameleon-like powers of embryonic stem cells, a startling breakthrough that might someday deliver the medical payoffs of embryo cloning without the controversy... MORE
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Skin Cells Made To Mimic Stem Cells
Scientists say method could ease ethical debate, open new era in medicine
By Alan Boyle
MSNBC, November 20, 2007
Two research groups have found different genetic recipes to give ordinary skin cells the power to turn into virtually any kind of human tissue, just as embryonic stem cells do... MORE
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Gladstone Scientist's Japan Lab Reprograms Human Adult Stem Cells
By Ron Leuty
San Francisco Business Times, November 20, 2007
Stem cell researcher Shinya Yamanaka—who arrived at the San Francisco labs of the J. David Gladstone Institutes this summer—said he and his Kyoto University colleagues in Japan successfully reprogrammed human adult cells to function like embryonic stem cells... MORE
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A New Town Begins To Take Root Within The City
By Ron Leuty
San Francisco Business Times, October 12, 2007
On a recent sunny afternoon, the management team of the J. David Gladstone Institutes took a little walk through a construction site, on a path winding along Mission Creek greenspace and across the Fourth Street bridge... MORE
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Blood Vessels Grown From Patient's Skin
By Lawrence K. Altman
The New York Times, October 9, 2007
From a snippet of a patient's skin, researchers have grown blood vessels in a laboratory and then implanted them to restore blood flow around the patient's damaged arteries and veins... MORE
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California Takes Lead in Stem Cell Research, Scientist Recruitment
Interview By Spencer Michels
PBS Newshour, October 8, 2007
Since California passed a $3 billion bond measure for stem cell research, recruitment of top scientists has outpaced every other state. The new funding has sparked the building of state-of-the-art facilities and a push for stem cell innovations... MORE
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Editorial:
Californians eagerly invest in stem cell research fund
The Mercury News, October 8, 2007
Three years after approving Proposition 71, Californians proved last week they haven't lost their enthusiasm for stem cell research.
State officials expected individual investors to snap up about $30 million of the $250 million in bonds for research that went on sale Wednesday. Instead, they swamped brokers with requests until $103 million were sold... MORE
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Stem Cell Bond Sales Open To Public:
Will Help Fund Institute
By Terry McSweeney
KGO-TV ABC-7 News, October 3, 2007
Passage of the $3 billion proposition to invest in human embryonic stem cell research put California in the world spotlight. Today individuals can put their money where their vote was. This ABC-TV Report features Gladstone Institute of Cardiovascular Disease director, Dr. Deepak Srivastava... MORE
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INTERVIEW:
New Mechanism to Explain Memory Loss in Alzheimer's
By John Sterling
Genetic Engineering & Biotechnology News, September 20, 2007
GEN's Editor-in-Chief John Sterling interviews Dr. Lennart Mucke from the Gladstone Institute of Neurological Disease... MORE
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Applying Existing Medications To Alzheimer's
By Carolyn Tyler
KGO-TV ABC7 News, Sep. 6, 2007
In the near future, medicine already available for other conditions could be used for Alzheimer's.
Scientists...have long known that something called amyloid protein builds up in the brains of Alzheimer's patients.
Now, researchers at the Gladstone Institute in San Francisco have made a discovery about the possible role of amyloids.
CLICK TO VIEW
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Money Changes Everything:
Stem cell measure draws top researchers to California through promise of funding
By Daniel S. Levine
The Journal of Life Sciences, August 20, 2007
By most estimates, it will be years before any cures emerge from the research funded by California's $3-billion stem cell measure approved in 2004. But already, the funding has changed the landscape for stem cell research by drawing top scientists to the Golden State... MORE
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San Francisco Lab for Stem-cell Pioneer
By Mary Anne Ostrom
MercuryNews.com, August 16, 2007
A Japanese pioneer in stem-cell research is opening a lab in San Francisco, a significant milestone in the state's bid to become an international draw for the world's leading regenerative medicine experts... MORE
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Japanese Stem Cell Expert Will Join a San Francisco University
By Rob Waters
Bloomberg.com, August 16, 2007
Shinya Yamanaka, who pioneered a way to allow adult stem cells to revert to a more primitive state so they act more like cells from embryos, is joining the University of California, San Francisco... MORE
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New Gladstone Institutes Star Hopes to Create Stem Cells In a New Way
MSN Money From BizJournals, August 16, 2007
Dr. Shinya Yamanaka, introduced Thursday as the latest star scientist to join the J. David Gladstone Institutes in San Francisco, hopes to reprogram human cells to create embryonic stem cells in the next year or two... MORE
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Beer Gut Check:
Study Sizes Up Belly Fat
By Sarah Baldauf
U.S. News & World Report, July 24, 2007
An apple–shaped body with a wide waistline will have anyone's doctor pushing an exercise regimen and healthier eating. Pear–shaped people, meanwhile, may get a break. That's because, as researchers are learning, all fat tissue is not equivalent in health terms... MORE
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Breakthrough In Stem Cell Production
By Carolyn Johnson
ABC-TV KGO Channel 7 News, June 6, 2007
Of mice and medicine. Science makes a major advance in stem cell research by turning back the clock. They've taken adult cells in mice and turned them into the building blocks of life.
CLICK TO VIEW
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Dr. Deepak Srivastiva, director of the Gladstone Institute of Cardiovascular Disease, is featured in an episode of the TV science series Quest, a production of KQED-TV in San Francisco.
See the entire program on your local PBS station. The episode debuts on May 29th at 7:30p.m., pacific time. Check your local listings.
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Reducing one protein prevents Alzheimer's symptoms in mice
By Dr. Susan Sharma
Insider Medicine, May 9, 2007
Lowering the level of one protein involved in Alzheimer's disease appears to prevent some of its disabling symptoms, according to a report published in the journal Science.
CLICK TO VIEW
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Strategy Could Put Brakes on Alzheimer's
By Amanda Gardner [Health Day Reporter]
Washington Post, May 4, 2007
By cutting levels of a brain protein called “tau,” scientists were able to preserve the memory and lifespans of mice genetically engineered to develop Alzheimer's disease... MORE
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Discovery by Gladstone Scientists Suggests New Treatment Strategy for Chronic Brain Diseases
KTVU-TV, May 4, 2007
Drs. Lennart Mucke and Erik Roberson of the Gladstone Institute of Neurological Disease have found that reducing levels of the protein tau protects the brain from the harmful effects of amyloid-beta toxicity...
 Play the Video
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Express Yourself:
A Conversation with Chris Barker, Director of the Genomics Core Laboratory
By Jeff Miller
UCSF Science Café, March 16, 2007
Modern science feeds on ideas. But ideas without technology are like a chef without a fully equipped kitchen. You can't taste success without testing it first.... MORE
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Nonprofit profile
The J. David Gladstone institutes
Robert W. Mahley, President and senior investigator
San Francisco Business Times, February 23, 2007
By Sarah Duxbury
The San Francisco Business Times offers this profile of Gladstone as told by Dr. Robert W. Mahley... MORE
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Ace of Hearts:
A Conversation with Developmental Biologist and Cardiologist Deepak Srivastava
By Jeff Miller
UCSF Science Café, February 16, 2007
Deepak Srivastava, MD, remembers his first broken heart. It came from a frog.
"It happened in my high school biology class. I had to dissect out a frog heart and when I did, it continued to beat in the petri dish...." MORE
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Inside New Stem Cell Research
KGO ABC-TV, February 16, 2007
Now that the grants are being given out, there are great expectations in the field of stem cell research. But how quickly will this research turn into reality, or how long before stem cells will help people with Alzheimer's or other diseases?.... MORE
 Play the Video [WMV]
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HIV Takes A Punch
Clearer picture of how antibodies bind to HIV surface protein could lead to vaccine
By Sarah Everts
Chemical & Engineering News, February 15, 2007
A chink discovered in HIV's seemingly impenetrable armor may provide the structural insights needed to develop a vaccine..... MORE
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Gladstone Institutes Places High Value on Collaboration, Communication, Staff Support
Business and Legal Reports, February 3, 2007
The J. David Gladstone Institutes, a private, nonprofit biomedical research organization, placed number two on The Scientist Magazine's list of Best Places toWork in Academia in October 2006, up from third place in 2005. A collaborative culture, support for gifted scientists, postdoctoral fellows, and their work is the key to Gladstone's success. ... MORE
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A vaccine development ‘renaissance’
Technology, boosted funding and higher profits are a shot in the arm for development.
By Daniel Costello
Los Angeles Times, January 28, 2007
Breakthroughs in technology, increased funding and higher profits are spurring a boom in vaccine discovery and development that could save or improve the lives of millions of people by attacking such scourges as cancer and malaria.... MORE
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Persistence breeds optimism in the research laboratories
Amyloid hypothesis considered central to the quest for drugs and vaccines
By Mike Funston
Toronto Star, Jan 25, 2007
The task is daunting, but Toronto researcher Dr. Paul Fraser sounds optimistic about the quest for effective Alzheimer's disease treatments.... MORE
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