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The mission of the Gladstone Institute of Cardiovascular Disease is to contribute to the health and welfare of humankind through research into the causes and prevention of cardiovascular disease.

Director: Deepak Srivastava, M.D. ••• 1650 Owens Street, San Francisco, CA 94158
Tel: (415) 734-2716 ••• Fax: (415) 355-0960

In the News Featured Articles

Gladstone's Shinya Yamanaka Wins “Baby Nobel”

Shinya Yamanaka

April 8, 2009—Shinya Yamanaka, MD, PhD, of the Gladstone Institutes and Kyoto University is one of seven recipients of Canada's prestigious Gairdner Award. The Gairdner is referred to as the “Baby Nobel,” since many winners then go on to win the Nobel Prize. See press release.

Gladstone Scientists Identify Key Factors in Heart Cell Creation

April 26, 2009—Scientists at the Gladstone Institute of Cardiovascular Disease have identified for the first time key genetic factors that drive the process of generating new heart cells. See press release.

FARESE: Deficiency of the intestinal enzyme acyl CoA: monoacylglycerol acyltransferase-2 protects mice from metabolic disorders induced by high-fat feeding

FARESE: Retinol Esterification by DGAT1 Is Essential for Retinoid Homeostasis in Murine Skin

SRIVASTAVA: Cardiac Fibroblasts Regulate Myocardial Proliferation through beta-1 Integrin Signaling

POLLARD: A Genome-Wide Approach to Identifying Novel-Imprinted Genes

SRIVASTAVA: miR-126 Regulates Angiogenic Signaling and Vascular Integrity

YAMANAKA: Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors

CONKLIN: WikiPathways: Pathway Editing for the People

BRUNEAU: The Developmental Genetics of Congenital Heart Disease

YAMANAKA: Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells

CHARO: A chemokine receptor essential for mobilization of monocytes from bone marrow during hypercholesterolemia

What Makes Us Human?
Comparisons of the genomes of humans and chimpanzees are revealing those rare stretches of DNA that are ours alone

Scientific American cover

Katherine S. Pollard's work on what tiny genetic changes say about our evoluation was featured on the cover of the May 2009 issue of Scientific American. See article.

International Society for Stem Cell Research educational video contest winners!!!

Mark White, Kathy Ivey, and Josh Arbold created a short educational video, explaining the fundamentals of stem cells, to be used in conjunction with the Gladstone high school and community outreach programs. In addition, this video was selected as the winner of educational stem cell video contest conducted by the ISSCR.

See news archives for previous stories featured here.
Research Topics

Atherosclerosis: Cholesterol, Inflammation, and Obesity

Genetic Networks in Cardiac Development and Stem Cell Biology

Nuclear Reprogramming to Induce Pluripotency

Faculty Recruitment
The Gladstone Instituteof Cardiovascular Diseaseis currently recruiting new faculty in the areas of
stem cell and developmental biology
and
cardiovascular genetics.
See posting for further details.


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