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2003

Aiyagari AL, Taylor BR, Aurora V, Young SG, Shannon KM (2003) Hematologic effects of inactivating the Ras processing enzyme Rce1. Blood 101:2250–2252.

Alexander S, Srinivasan S, Alexander H (2003) Proteomics opens doors to the mechanisms of developmentally regulated secretion. Mol. Cell. Proteomics 2:1156–1163.

Barczak A, Rodriguez MW, Hanspers K, Koth LL, Tai YC, Bolstad BM, Speed TP, Erle DJ (2003) Spotted long oligonucleotide arrays for human gene expression analysis. Genome Res. 13:1775–1785.

Beigneux AP, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR (2003) Sick euthyroid syndrome is associated with decreased TR expression and DNA binding in mouse liver. Am. J. Physiol. Endocrinol. Metab. 284:E228–E236.

Bersot TP, Pépin GM, Mahley RW (2003) Risk determination of dyslipidemia in populations characterized by low levels of high-density lipoprotein cholesterol. Am. Heart J. 146:1052–1060.

Charo IF, Peters W (2003) Chemokine receptor 2 (CCR2) in atherosclerosis, infectious diseases, and regulation of T-cell polarization. Microcirculation10:259–264.

Chen HC, Jensen DR, Myers HM, Eckel RH, Farese RV Jr (2003) Obesity resistance and enhanced glucose metabolism in mice transplanted with white adipose tissue lacking acyl CoA:diacylglycerol acyltransferase 1. J. Clin. Invest. 111:1715–1722.

Chen HC, Ladha Z, Smith SJ, Farese RV Jr (2003) Analysis of energy expenditure at different ambient temperatures in mice lacking DGAT1. Am. J. Physiol. Endocrinol. Metab. 284:E213–E218.

Doniger SW, Salomonis N, Dahlquist KD, Vranizan K, Lawlor SC, Conklin BR (2003) MAPPFinder: Using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data. Genome Biol. 4:R7.

Gharaee-Kermani M, McCullumsmith RE, Charo IF, Kunkel SL, Phan SH (2003) CC-chemokine receptor 2 required for bleomycin-induced pulmonary fibrosis. Cytokine 24:266–276.

Gohil K, Schock BC, Chakraborty AA, Terasawa Y, Raber J, Farese RV Jr, Packer L, Cross CE, Traber MG (2003) Gene expression profile of oxidant stress and neurodegeneration in transgenic mice deficient in α-tocopherol transfer protein. Free Radic. Biol. Med. 35:1343–1354.

Hanson CL, Ilag LL, Malo J, Hatters DM, Howlett GJ, Robinson CV (2003) Phospholipid complexation and association with apolipoprotein C-II: Insights from mass spectrometry. Biophys. J. 85:3802–3812.

Harris FM, Brecht WJ, Xu Q, Tesseur I, Kekonius L, Wyss-Coray T, Fish JD, Masliah E, Hopkins PC, Scearce-Levie K, Weisgraber KH, Mucke L, Mahley RWM, Huang Y (2003) Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer’s disease-like neurodegeneration and behavioral deficits in transgenic mice. Proc. Natl. Acad. Sci. USA 100:10996–10971.

Hersberger M, Patarroyo-White S, Qian X, Arnold KS, Rohrer L, Balestra ME, Innerarity TL (2003) Regulatable liver expression of the rabbit apolipoprotein B mRNA-editing enzyme catalytic polypeptide 1 (APOBEC-1) in mice lacking endogenous APOBEC-1 leads to aberrant hyperediting. Biochem. J. 369:255–262.

Kasravi FB, Brecht WJ, Weisgraber KH, Harris HW (2003) Induction of cytokine tolerance requires internalization of chylomicron-bound LPS into hepatocytes. J. Surg. Res. 115:303–309.

Kasravi FB, Welch WJ, Peters-Libeu CA, Weisgraber KH, Harris HW (2003) Induction of cytokine tolerance in rodent hepatocytes by chylomicron-bound LPS is low-density lipoprotein receptor dependent. Shock 19:157–162.

Lesnik P, Haskell CA, Charo IF (2003) Decreased atherosclerosis in CX3CR1–/– mice reveals a role for fractalkine in atherogenesis. J. Clin. Invest. 111:333–340.

Liao W, Hui TY, Young SG, Davis RA (2003) Blocking microsomal triglyceride transfer protein interferes with apoB secretion without causing retention or stress in the ER. J. Lipid Res. 44:978–985.

Lieu HD, Withycombe SK, Walker Q, Rong JX, Walzem RL, Wong JS, Hamilton RL, Fisher EA, Young SG (2003) Eliminating atherogenesis in mice by switching off hepatic lipoprotein secretion. Circulation. 107:1315–1321.

Listenberger LL, Han X, Lewis SE, Cases S, Farese RV Jr, Ory DS, Schaffer JE (2003) Triglyceride accumulation protects against fatty acid-induced lipotoxicity. Proc. Natl. Acad. Sci. USA 100:3077–3082.

Mahley RW, Huang Y (2003) Apolipoprotein E: Structure and function in lipid metabolism and neurobiology. In The Molecular and Genetic Basis of Neurologic and Psychiatric Disease (Rosenberg RN, Prusiner SB, DiMauro S, Barchi RL, Nestler EJ, eds) 3rd Ed, pp. 565–573, Butterworth Heinemann, Philadelphia.

Mahley RW, Weisgraber KH, Farese RV Jr (2003) Disorders of lipid metabolism. In Williams Textbook of Endocrinology (Larsen PR, Kronenberg HM, Melmed S, Polonsky KS, eds) 10th Ed, pp. 1642–1705, Saunders, Philadelphia.

Maske CP, Hollinshead MS, Higbee NC, Bergo MO, Young SG, Vaux DJ (2003) A carboxyl-terminal interaction of lamin B1 is dependent on the CAAX endoprotease Rce-1 and carboxymethylation. J. Cell Biol. 162:1223–1232.

McCormick SPA, Liu CYY, Young SG, Nielsen LB (2003) Manipulating large insert clones for transgenesis. Methods Mol. Biol. 209:105–123.

Peters W, Ernst JD (2003) Mechanisms of cell recruitment in the immune response to Mycobacterium tuberculosis. Microbes Infect. 5:151–158.

Raffaï RL, Hasty AH, Wang Y, Mettler SE, Sanan DA, Linton MF, Fazio S, Weisgraber KH (2003) Hepatocyte-derived apoE is more effective than non-hepatocyte-derived apoE in remnant lipoprotein clearance. J. Biol. Chem. 278: 11670–11675.

Raffaï RL, Weisgraber KH (2003) Cholesterol: From heart attacks to Alzheimer’s disease. J. Lipid Res. 44:1423–1430.

Raffaï RL, McPherson R, Weisgraber KH, Innerarity TL, Rassart E, Bersot TP, Milne RW (2003) Antibody phenotyping test for the human apolipoprotein E2 isoform. Clin. Chem. 49:1524–1526.

Saito H, Dhanasekaran P, Baldwin F, Weisgraber KH, Phillips MC, Lund-Katz S (2003) Effects of polymorphism on the lipid interaction of human apolipoprotein E. J. Biol. Chem. 278:40723–40729.

Saito H, Dhanasekaran P, Nguyen D, Baldwin F, Weisgraber KH, Wehrli S, Phillips MC, Lund-Katz S (2003) Characterization of the heparin binding sites in human apolipoprotein E. J. Biol. Chem.278:14782–14787.

Santiago-García J, Kodama T, Pitas RE (2003) The class A scavenger receptor binds to proteoglycans and mediates adhesion of macrophages to the extracellular matrix. J. Biol. Chem. 278:6942–6946.

Segal MR, Dahlquist KD, Conklin BR (2003) Regression approaches for microarray data analysis. J. Comput. Biol. 10:961–980.

Srinivasan S, Vaisse C, Conklin BR (2003) Engineering the melanocortin-4 receptor to control Gs signaling in vivo. Ann. N.Y. Acad. Sci. 994:225–232.

Stein O, Dabach Y, Ben-Naim M, Halperin G, Charo IF, Stein Y (2003) In CCR2–/– mice monocyte recruitment and egress of LDL cholesterol in vivo is impaired. Biochem. Biophys. Res. Commun. 300:477–481.

Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L’Italien L, Chuang P-T, Young SG, Skarnes WC, Babbitt PC, Ferrin TE (2003) BayGenomics: A resource of insertional mutations in mouse embryonic stem cells. Nucleic Acids Res. 31:278–281.

Tsutsumi C, Sonoda K-H, Egashira K, Qiao H, Hisatomi T, Nakao S, Ishibashi M, Charo IF, Sakamoto T, Murata T, Ishibashi T (2003) The critical role of ocular-infiltrating macrophages in the development of choroidal neovascularization. J. Leukoc. Biol. 74:25–32.

Wang X, Chauhan V, Nguyen AT, Schultz J, Davignon J, Young SG, Borén J, Innerarity TL, Rutai H, Milne RW (2003) Immunochemical evidence that human apoB differs when expressed in rodent versus human cells. J. Lipid Res.44:547–553.

Willner EL, Tow B, Buhman KK, Wilson M, Sanan DA, Rudel LL, Farese RV Jr (2003) Deficiency of acyl CoA:cholesterol acyltransferase 2 prevents atherosclerosis in apolipoprotein E-deficient mice. Proc. Natl. Acad. Sci. USA 100:1262–1267.

Winter-Vann AM, Kamen BA, Bergo MO, Young SG, Melnyk S, James SJ, Casey PJ (2003) Targeting Ras signaling through inhibition of carboxyl methylation: An unexpected property of methotrexate. Proc. Natl. Acad. Sci. USA 100:6529–6534.

Yen C-LE, Farese RV Jr (2003) MGAT2, a monoacylglycerol acyltransferase expressed in the small intestine. J. Biol. Chem.278:18532–18537.

Zambon AC, McDearmon EL, Salomonis N, Vranizan KM, Johansen KL, Adey D, Takahashi JS, Schambelan M, Conklin BR (2003) Time- and exercise-dependent gene regulation in human skeletal muscle. Genome Biol. 4:R61.

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