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Publications 2012
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Arrasate M, Finkbeiner S. Protein aggregates in Huntington’s disease.
Exp. Neurol.
In press.
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Baeza-Raja B, Li P, Le Moan N, Sachs BD, Schachtrup C, Davalos D, Vagena E, Bridges D, Kim C, Saltiel AR, Olefsky JM, Akassoglou K (2012) p75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivity.
Proc. Natl. Acad. Sci. U S A.
In press.
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Bien-Ly N, Gillespie AK, Walker D, Yoon SY, Huang Y (2012) Reducing Human Apolipoprotein E Levels Attenuates Age-Dependent Aβ Accumulation in Mutant Human Amyloid Precursor Protein Transgenic Mice.
J. Neurosci.
32:4803–4811.
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Davalos D, Akassoglou K (2012) Fibrinogen as a key regulator of inflammation in disease.
Semin. Immunopathol.
34:43–62.
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Davalos D, Akassoglou K. In vivo of the mouse spinal cord using two-photon microscopy.
J. Vis. Exp.
In press.
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Finkbeiner S. Combining automated microscopy with statistics. In:
Physical Cell Biology: Closing the Gap.
Eds. Brown WE, Howard, GC. New York: Oxford University Press. In press.
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Fong H, Wong RC, Donovan PJ (2012) Transcriptional regulation of TRKC by SOX2 in human embryonic stem cells.
Stem Cell Res.
8:206–214.
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Kwan W, Magnusson A, Chou A, Adame A, Carson MJ, Kohsaka S, Masliah E, Möller T, Ransohoff R, Tabrizi SJ, Björkqvist M, Muchowski PJ (2012) Bone marrow transplantation confers modest benefits in mouse models of Huntington's disease.
J. Neurosci.
32:133–142.
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Le Moan N, Baeza-Raja B, Akassoglou K. p75 (NTR) and hypoxia: A breath of fresh air in neurotrophin receptor signaling.
Cell Cycle
In press.
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Lerner TN, Kreitzer AC (2012) RGS4 is required for dopaminergic control of striatal LTD and susceptibility to parkinsonian motor deficits.
Neuron
73:347–359.
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Minami SS, Sun B, Popat K, Kauppinen T, Pleiss M, Zhou Y, Ward ME, Floreanig P, Mucke L, Desai T, Gan L. Selective targeting of microglia by quantum dots.
J. Neuroinflammation
In press.
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Huang Y, Mucke L (2012) Alzheimer mechanisms and therapeutic strategies.
Cell
146:1204-1222.
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Javier RM, Kreitzer AC (2012) Dendritic architecture: Form and function.
Nat. Neurosci.
15:503-505.
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Pearn ML, Hu Y, Niesman IR, Patel HH, Drummond JC, Roth DM, Akassoglou K, Patel PM, Head BP (2012) Propofol neurotoxicity is mediated by p75 neurotrophin receptor activation.
Anesthesiology
116:352–361.
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Peters-Libeu C, Miller J, Rutenber E, Newhouse Y, Krishnan P, Cheung K, Hatters D, Brooks E, Widjaja K, Tran T, Mitra S, Arrasate M, Mosquera LA, Taylor D, Weisgraber KH, Finkbeiner S. Disease-associated polyglutamine stretches in monomeric huntingtin adopt a compact structure.
J. Mol. Biol.
In press.
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Sancenon V, Lee SA, Patrick C, Griffith J, Paulino A, Outeiro TF, Reggiori F, Masliah E, Muchowski PJ. Suppression of α-synuclein toxicity and vesicle trafficking defects by phosphorylation at S129 in yeast depends on genetic context.
Hum. Mol. Genet.
In press.
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Sharma P, Ando M, Daub A, Kaye J, Finkbeiner S (2012) High-throughput screening in primary neurons.
Meth. Enzymol.
506:331–360.
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Verret L, Mann EO, Hang GB, Barth A, Cobos I, Ho K, Devidze N, Masaliah E, Kreitzer AC, Mody I, Mucke L, Palop JJ. Key role of interneuronal impairments in Alzheimer's disease-related neural network and cognitive dysfunction.
Cell
In press.
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Wray S, Self M, Lewis PA, Taanman JW, Ryan N, Mahoney C, Devine MJ, Sheerin UM, Houlden H, Morris H, Healy D, Marti-Masso JF, Sutherland M, Shapira AJ, Uitti RJ, Guttman M, Opala G, Jasinska-Myga B, Puschmann A, Nilsson C, Guttmann L, Boeve B, Boylan K, Stoessl J, Gerpen JV, Gerstenhaber M, Gwinn K, Dawson T, Isacson O, Marder K, Przedborski S, Finkbeiner S, Rothstein JD, Wszolek Z, Rossor M, Hardy J. Creation of an open-access mutation-defined fibroblast resource for neurological disease research.
PLoS One
In press.
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Yoshiike Y, Yamashita S, Mizoroki T, Maeda S, Murayama M, Kimura T, Sahara N, Soeda Y, Takashima A (2011) Adaptive responses to alloxan-induced mild oxidative stress ameliorates certain tauopathy phenotypes.
Aging Cell
11:51–62.
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