Lennart Mucke, MD
Director
Gladstone Institute of Neurological Disease
Joseph B. Martin Distinguished Professor of Neuroscience
University of California, San Francisco
Interests/Approaches: Alzheimer's disease, amyloid proteins, mechanisms of neurodegeneration, cognitive functions and their disruption by disease, glia, preclinical assessment of novel therapeutic strategies, transgenic models.
Steven M. Finkbeiner, MD, PhD
Associate Director and Associate Investigator
Gladstone Institute of Neurological Disease
Associate Professor of Neurology and Physiology
University of California, San Francisco
Interests/Approaches: astroglial-neuronal communication, calcium imaging, confocal microscopy, Huntington's disease, gene gun, neuroplasticity, neurotrophins, organotypic cultures, trinucleotide-repeat diseases.
Li Gan, PhD
Staff Research Investigator
Gladstone Institute of Neurological Disease
Assistant Professor of Neurology
University of California, San Francisco
Interests/Approaches: Alzheimer's disease, microglial-neuronal interaction, RNA interference, gene silencing, viral vector-mediated gene transfer, neurodegeneration, transgenic models, preclinical validation of novel therapeutic targets
Fen-Biao Gao, PhD
Associate Investigator
Gladstone Institute of Neurological Disease
Associate Professor of Neurology
University of California, San Francisco
Interests/Approaches: Frontotemporal dementia, neurodevelopmental disorders, neuronal development, microRNAs, fly genetics, in vivo imaging, human stem cells.
Yadong Huang, MD, PhD
Assistant Investigator
Gladstone Institute of Neurological Disease
Assistant Professor of Pathology and Neurology
University of California, San Francisco
Interests/Approaches: Alzheimer's disease, apoE, brain lipid metabolism, cytoskeletal structure and function, neurodegeneration, proteases, protease inhibitors, tau protein, transgenic models.
Anatol Kreitzer, PhD
Assistant Investigator
Gladstone Institute of Neurological Disease
Assistant Professor of Physiology and Neurology
University of California, San Francisco
Interests/Approaches: Basal ganglia, dopamine, electrophysiology, endocannabinoids, Huntington's disease, movement disorders, neural circuits and behavior, optical imaging, Parkinson's disease, striatum, synaptic plasticity.
Robert W. Mahley, MD, PhD
President, The J. David Gladstone Institutes
Senior Investigator, Gladstone Institute of Neurological Disease
Professor of Pathology and Medicine
University of California, San Francisco
Interests/Approaches: Alzheimer's disease, apoE, cell biology, cytoskeleton, DNA chips, lipid transport, proteoglycans.
Paul Muchowski, PhD
Associate Investigator
Gladstone Institute of Neurological Disease
Associate Professor of Biochemistry, Biophysics, and Neurology
University of California, San Francisco
Interests/Approaches: Protein misfolding, mechanisms of neurodegeneration, yeast genetic and chemical-genetic screens, atomic force microscopy, chaperone proteins.
Karl H. Weisgraber, PhD
Senior Investigator
Gladstone Institute of Neurological Disease
Professor of Pathology
University of California, San Francisco
Interests/Approaches: Alzheimer's disease, amyloidogenesis, apoE, crystallography, domain interaction, structure-function relationships.
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