Gladstone Home blank GIVI HOME
 
spacer
GIVI HOME

Gladstone Institutes Home  
Institute of
Cardiovascular Disease
GICD
 
Institute of
Neurological Disease
GIND
 
Center for
Translational
Research
CTR
University of California,
San Francisco
UCSF
 
Supporting Gladstone
Publications 2001
  • Chan SY, Empig CJ, Welte FJ, Speck RF, Schmaljohn A, Kreisberg JF, Goldsmith MA (2001) Folate receptor-a is a cofactor for cellular entry by Marburg and Ebola viruses. Cell 106:117–126.

  • Chen L-F, Fischle W, Verdin E, Greene WC (2001) Duration of nuclear NF-kB action regulated by reversible acetylation. Science 293:1653–1657.

  • de Noronha CMC, Sherman MP, Lin HW, Cavrois MV, Moir RD, Goldman RD, Greene WC (2001) Dynamic disruptions in nuclear envelope architecture and integrity induced by HIV-1 Vpr. Science 294:1105–1108.

  • Deeks SG, Wrin T, Liegler T, Hoh R, Hayden M, Barbour JD, Hellmann NS, Petropoulos CJ, McCune JM, Hellerstein MK, Grant RM (2001) Virologic and immunologic consequences of discontinuing combination antiretroviral-drug therapy in HIV-infected patients with detectable viremia. N. Engl. J. Med. 344:472–480.

  • Eckstein DA, Penn ML, Korin YD, Scripture-Adams DD, Zack JA, Kreisberg JF, Roederer M, Sherman MP, Chin PS, Goldsmith MA (2001) HIV-1 actively replicates in naïve CD4+ T cells residing within human lymphoid tissues. Immunity 15:671–682.

  • Eckstein DA, Sherman MP, Penn ML, Chin PS, De Noronha CMC, Greene WC, Goldsmith MA (2001) HIV-1 Vpr enhances viral burden by facilitating infection of tissue macrophages but not nondividing CD4+ T cells. J. Exp. Med. 194:1407–1419.

  • Fischle W, Dequiedt F, Fillion M, Hendzel MJ, Voelter W, Verdin E (2001) Human HDAC7 histone deacetylase activity is associated with HDAC3 in vivo. J. Biol. Chem. 276:35826–35835.

  • Fischle W, Kiermer V, Dequiedt F, Verdin E (2001) The emerging role of class II histone deacetylases. Biochem. Cell Biol. 79:337–348.

  • García F, Plana M, Ortiz GM, Bonhoeffer S, Soriano A, Vidal C, Cruceta A, Arnedo M, Gil C, Pantaleo G, Pumarola T, Gallart T, Nixon DF, Miró JM, Gatell JM (2001) The virological and immunological consequences of structured treatment interruptions in chronic HIV-1 infection. AIDS 15:F29–F40.

  • Geleziunas R, Xu W, Takeda K, Ichijo H, Greene WC (2001) HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell. Nature 410:834–838.

  • Hioe CE, Tuen M, Chien PC, Jr., Jones G, Ratto-Kim S, Norris PJ, Moretto WJ, Nixon DF, Gorny MK, Zolla-Pazner S (2001) Inhibition of human immunodeficiency virus type 1 gp120 presentation to CD4 T cells by antibodies specific for the CD4 binding domain of gp120. J. Virol. 75:10950–10957.

  • Jacobson MA, Schrier R, McCune JM, Torriani FJ, Holland GN, O’Donnell JJ, Freeman WR, Bredt BM (2001) Cytomegalovirus (CMV)–specific CD4+ T lymphocyte immune function in long-term survivors of AIDS-related CMV end-organ disease who are receiving potent antiretroviral therapy. J. Infect. Dis. 183:1399–1404.

  • Jordan A, Defechereux P, Verdin E (2001) The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation. EMBO J. 20:1726–1738.

  • Keppler OT, Yonemoto W, Welte FJ, Patton KS, Iacovides D, Atchison RE, Ngo T, Hirschberg DL, Speck RF, Goldsmith MA (2001) Susceptibility of rat-derived cells to replication by human immunodeficiency virus type 1. J. Virol. 75:8063–8073.

  • Komanduri KV, Donahoe SM, Moretto WJ, Schmidt DK, Gillespie G, Ogg GS, Roederer M, Nixon DF, McCune JM (2001) Direct measurement of CD4+ and CD8+ T-cell responses to CMV in HIV-1-infected subjects. Virology 279:459–470.

  • Komanduri KV, Feinberg J, Hutchins RK, Frame RD, Schmidt DK, Viswanathan MN, Lalezari JP, McCune JM (2001) Loss of cytomegalovirus-specific CD4+ T cell responses in human immunodeficiency virus type 1–infected patients with high CD4+ T cell counts and recurrent retinitis. J. Infect. Dis. 183:1285–1289.

  • Komanduri KV, McCune JM (2001) The diversity of T cells. N. Engl. J. Med. 344:231.

  • Komanduri KV, McCune JM (2001) Development and reconstitution of T-lymphoid immunity. In: Retroviral Immunology. Immune Response and Restoration (Walker BD, eds) Humana Press, Totowa, NJ, pp 79–107.

  • Kreisberg JF, Kwa D, Schramm B, Trautner V, Connor R, Schuitemaker H, Mullins JI, van't Wout AB, Goldsmith MA (2001) Cytopathicity of human immunodeficiency virus type 1 primary isolates depends on coreceptor usage and not patient disease status. J. Virol. 75:8842–8847.

  • Kruhlak MJ, Hendzel MJ, Fischle W, Bertos NR, Hameed S, Yang X-J, Verdin E, Bazett-Jones DP (2001) Regulation of global acetylation in mitosis through loss of histone acetyltransferases and deacetylases from chromatin. J. Biol Chem. 276:38307–38319.

  • Liegler TJ, Hayden MS, Lee KH, Hoh R, Deeks SG, Grant RM (2001) Protease inhibitor-resistant HIV-1 from patients with preserved CD4 cell counts is cytopathic in activated CD4 T lymphocytes. AIDS 15:179–184.

  • Maecker HT, Dunn HS, Suni MA, Khatamzas E, Pitcher CJ, Bunde T, Persaud N, Trigona W, Fu T-M, Sinclair E, Bredt BM, McCune JM, Maino VC, Kern F, Picker LJ (2001) Use of overlapping peptide mixtures as antigens for cytokine flow cytometry. J. Immunol. Methods 255:27–40.

  • McCune JM (2001) The dynamics of CD4+ T-cell depletion in HIV disease. Nature 410:974–979.

  • McDermott AB, Spiegel HML, Irsch J, Ogg GS, Nixon DF (2001) A simple and rapid magnetic bead separation technique for the isolation of tetramer-positive virus-specific CD8 T cells. AIDS 15:810–812.

  • Mori N, Ueda A, Geleziunas R, Wada A, Hirayama T, Yoshimura T, Yamamoto N (2001) Induction of monocyte chemoattractant protein 1 by Helicobacter pylori involves NF-kB. Infect. Immun. 69:1280–1286.

  • Napolitano LA, Grant RM, Deeks SG, Schmidt D, De Rosa SC, Herzenberg LA, Herndier BG, Andersson J, McCune JM (2001) Increased production of IL-7 accompanies HIV-1–mediated T-cell depletion: Implications for T-cell homeostasis. Nat. Med. 7:73–79.

  • Ortiz GM, Wellons M, Brancato J, Vo HTT, Zinn RL, Clarkson DE, Van Loon K, Bonhoeffer S, Miralles GD, Montefiori D, Bartlett JA, Nixon DF (2001) Structured antiretroviral treatment interruptions in chronically HIV-1-infected subjects. Proc. Natl. Acad. Sci. USA 98:13288–13293.

  • Penn ML, Myers M, Eckstein DA, Liegler TJ, Hayden M, Mammano F, Clavel F, Deeks SG, Grant RM, Goldsmith MA (2001) Primary and recombinant HIV type 1 strains resistant to protease inhibitors are pathogenic in mature human lymphoid tissues. AIDS Res. Hum. Retroviruses 17:517–523.

  • Price RW, Paxinos EE, Grant RM, Drews B, Nilsson A, Hoh R, Hellmann NS, Petropoulos CJ, Deeks SG (2001) Cerebrospinal fluid response to structured treatment interruption after virological failure. AIDS 15:1–10.

  • Rose NF, Marx PA, Luckay A, Nixon DF, Moretto WJ, Donahoe SM, Montefiori D, Roberts A, Buonocore L, Rose JK (2001) An effective AIDS vaccine based on live attenuated vesicular stomatitis virus recombinants. Cell 106:539–549.

  • Sandberg JK, Fast NM, Nixon DF (2001) Functional heterogeneity of cytokines and cytolytic effector molecules in human CD8+ T lymphocytes. J. Immunol. 167:181–187.

  • Schaeffer E, Geleziunas R, Greene WC (2001) Human immunodeficiency virus type 1 Nef functions at the level of virus entry by enhancing cytoplasmic delivery of virions. J. Virol. 75:2993–3000.

  • Sheehy ME, McDermott AB, Furlan SN, Klenerman P, Nixon DF (2001) A novel technique for the fluorometric assessment of T lymphocyte antigen specific lysis. J. Immunol. Methods 249:99–110.

  • Sherman MP, de Noronha CMC, Heusch MI, Greene S, Greene WC (2001) Nucleocytoplasmic shuttling by human immunodeficiency virus type 1 Vpr. J. Virol. 5:1522–1532.

  • Stoddart CA, Liegler TJ, Mammano F, Linquist-Stepps VD, Hayden MS, Deeks SG, Grant RM, Clavel F, McCune JM (2001) Impaired replication of protease inhibitor-resistant HIV-1 in human thymus. Nat. Med. 7:712–718.

  • Strizki JM, Xu S, Wagner NE, Wojcik L, Liu J, Hou Y, Endres M, Palani A, Shapiro S, Clader JW, Greenlee WJ, Tagat JR, McCombie S, Cox K, Fawzi AB, Chou C-C, Pugliese-Sivo C, Davies L, Moreno ME, Ho DD, Trkola A, Stoddart CA, Moore JP, Reyes GR, Baroudy BM (2001) SCH-C (SCH 351125), an orally bioavailable, small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivo. Proc. Natl. Acad. Sci. USA 98:12718–12723.

  • Teixeira L, Valdez H, McCune JM, Koup RA, Badley AD, Hellerstein MK, Napolitano LA, Douek DC, Mbisa G, Deeks S, Harris JM, Barbour JD, Gross BH, Francis IR, Halvorsen R, Asaad R, Lederman MM (2001) Poor CD4 T cell restoration after suppression of HIV-1 replication may reflect lower thymic function. AIDS 15:1749–1756.

  • Zhang K, Hawken M, Rana F, Welte FJ, Gartner S, Goldsmith MA, Power C (2001) Human immunodeficiency virus type 1 clade A and D neurotropism: Molecular evolution, recombination, and coreceptor use. Virology 283:19–30.


Gladstone Home | Cardiovascular Disease | Virology and Immunology | Neurological Disease | Administration | UCSF