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Supporting Gladstone
Publications 1999
  • Berkowitz RD, van't Wout AB, Kootstra NA, Moreno ME, Linquist-Stepps VD, Bare C, Stoddart CA, Schuitemaker H, McCune JM (1999) R5 strains of human immunodeficiency virus type 1 from rapid progressors lacking X4 strains do not possess X4-type pathogenicity in human thymus. J. Virol. 73:7817–7822.

  • Bresnahan PA, Yonemoto W, Greene WC (1999) Cutting edge: SIV Nef protein utilizes both leucine- and tyrosine-based protein sorting pathways for down-regulation of CD4. J. Immunol. 163:2977–2981.

  • Chan SY, Speck RF, Power C, Gaffen SL, Chesebro B, Goldsmith MA (1999) V3 recombinants indicate a central role for CCR5 as a coreceptor in tissue infection by human immunodeficiency virus type 1. J. Virol. 73:2350–2358.

  • Critchfield JW, Ho O, Roberts BD, Van Lint C, Verdin E, Butera ST (1999) Isoquinolinesulphonamide derivatives inhibit transcriptional elongation of human immunodeficiency virus type 1 RNA in a promyelocytic model of latency. Antiviral Chem. Chemother. 10:275–284.

  • Deeks SG, Grant RM (1999) Sustained CD4 responses after virological failure of protease inhibitor–containing therapy. Antiviral Ther. 4 (Suppl. 3):7–11.

  • Deeks SG, Hecht FM, Swanson M, Elbeik T, Loftus R, Cohen PT, Grant RM (1999) HIV RNA and CD4 cell count response to protease inhibitor therapy in an urban AIDS clinic: Response to both initial and salvage therapy. AIDS 13:F35–F43.

  • Deeks SG, Hellmann NS, Grant RM, Parkin NT, Petropoulos CJ, Becker M, Symonds W, Chesney M, Volberding PA (1999) Novel four-drug salvage treatment regimens after failure of a human immunodeficiency virus type 1 protease inhibitor–containing regimen: Antiviral activity and correlation of baseline phenotypic drug susceptibility with virologic outcome. J. Infect. Dis. 179:1375–1381.

  • Dittmer D, Stoddart C, Renne R, Linquist-Stepps V, Moreno ME, Bare C, McCune JM, Ganem D (1999) Experimental transmission of Kaposi's sarcoma–associated herpesvirus (KSHV/HHV-8) to SCID-hu Thy/Liv mice. J. Exp. Med. 190:1857–1868.

  • Fischle W, Emiliani S, Hendzel MJ, Nagase T, Nomura N, Voelter W, Verdin E (1999) A new family of human histone deacetylases related to Saccharomyces cerevisiae HDA1p. J. Biol. Chem. 274:11713–11720.

  • Gaffen SL, Lai SY, Longmore GD, Liu KD, Goldsmith MA (1999) Genetic evidence for an additional factor required for erythropoietin-induced signal transduction. Blood 94:74–86.

  • Geleziunas R, Greene WC (1999) Molecular insights into HIV-1 infection and pathogenesis. In: The Medical Management of AIDS (Volberding PA, eds) W.B. Saunders, Philadelphia, pp 23–39.

  • Gobbi A, Stoddart CA, Malnati MS, Locatelli G, Santoro F, Abbey NW, Bare C, Linquist-Stepps V, Moreno MB, Herndier BG, Lusso P, McCune JM (1999) Human herpesvirus 6 (HHV-6) causes severe thymocyte depletion in SCID-hu Thy/Liv mice. J. Exp. Med. 189:1953–1960.

  • Grant RM (1999) Advances in the diagnosis and evaluation of acute HIV 1 infection. In: Proceedings of the 1998 Conference on the Laboratory Science of HIV (eds) Centers for Disease Control and Prevention, Atlanta, pp 61–66.

  • Grant RM, Saag MS (1999) Laboratory testing for HIV-1. In: The Medical Management of AIDS (Volberding PA, eds) W.B. Saunders, Philadelphia, pp 43–65.

  • Hassoba HM, Bzowej N, Berenguer M, Kim M, Zhou S, Phung Y, Grant R, Pessoa MG, Wright TL (1999) Evolution of viral quasispecies in interferon-treated patients with chronic hepatitis C virus infection. J. Hepatol. 31:618–627.

  • Hellerstein M, Hanley MB, Cesar D, Siler S, Papageorgopoulos C, Wieder E, Schmidt D, Hoh R, Neese R, Macallan D, Deeks S, McCune JM (1999) Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans. Nat. Med. 5:83–89.

  • Heusch M, Lin L, Geleziunas R, Greene WC (1999) The generation of NF-kB2 p52: Mechanism and efficiency. Oncogene 18:6201–6208.

  • Jenkins M, Keir M, McCune JM (1999) Fas is expressed early in human thymocyte development but does not transmit an apoptotic signal. J. Immunol. 163:1195–1204.

  • Kovalev G, Duus K, Wang L, Lee R, Bonyhadi M, Ho D, McCune JM, Kaneshima H, Su L (1999) Induction of MHC class I expression on immature thymocytes in HIV-1-infected SCID-hu Thy/Liv mice: Evidence of indirect mechanisms. J. Immunol. 162:7555–7562.

  • Lin X, Cunningham ET, Jr., Mu Y, Geleziunas R, Greene WC (1999) The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-kB acting through the NF-kB-inducing kinase and IkB kinases. Immunity 10:271–280.

  • Mahlknecht U, Bucala R, Verdin E (1999) Assignment of the histone deacetylase gene (Hdac3) to mouse chromosome 18B3 by in situ hybridization. Cytogenet. Cell Genet. 84:192–193.

  • Mahlknecht U, Emiliani S, Najfeld V, Young S, Verdin E (1999) Genomic organization and chromosomal localization of the human histone deacetylase 3 gene. Genomics 56:197–202.

  • Mahlknecht U, Hoelzer D, Bucala R, Verdin E (1999) Cloning and characterization of the murine histone deacetylase (HDAC3). Biochem. Biophys. Res. Commun. 263:482–490.

  • Middleton SA, Barbone FP, Johnson DL, Thurmond RL, You Y, McMahon FJ, Jin R, Livnah O, Tullai J, Farrell FX, Goldsmith MA, Wilson IA, Jolliffe LK (1999) Shared and unique determinants of the erythropoietin (EPO) receptor are important for binding EPO and EPO mimetic peptide. J. Biol. Chem. 274:14163–14169.

  • Ott M, Schnslzer M, Garnica J, Fischle W, Emiliani S, Rackwitz H-R, Verdin E (1999) Acetylation of the HIV-1 Tat protein by p300 is important for its transcriptional activity. Curr. Biol. 9:1489–1492.

  • Penn ML, Grivel J-C, Schramm B, Goldsmith MA, Margolis L (1999) CXCR4 utilization is sufficient to trigger CD4+ T cell depletion in HIV-1-infected human lymphoid tissue. Proc. Natl. Acad. Sci. USA 96:663–668.

  • Poulin J-F, Viswanathan MN, Harris JM, Komanduri KV, Wieder E, Ringuette N, Jenkins M, McCune JM, SZkaly R-P (1999) Direct evidence for thymic function in adult humans. J. Exp. Med. 190:479–486.

  • Speck RF, Esser U, Penn ML, Eckstein DA, Pulliam L, Chan SY, Goldsmith MA (1999) A trans-receptor mechanism for infection of CD4-negative cells by human immunodeficiency virus type 1. Curr. Biol. 9:547–550.

  • Staprans S, Marlowe N, Glidden D, Novakovic-Agopian T, Grant RM, Heyes M, Aweeka F, Deeks S, Price RW (1999) Time course of cerebrospinal fluid responses to antiretroviral therapy: Evidence for variable compartmentalization of infection. AIDS 13:1051–1061.

  • Staprans SI, Dailey PJ, Rosenthal A, Horton C, Grant RM, Lerche N, Feinberg MB (1999) Simian immunodeficiency virus disease course is predicted by the extent of virus replication during primary infection. J. Virol. 73:4829–4839.

  • Stoddart CA (1999) The SCID-hu Thy/Liv mouse: An animal model for HIV-1 infection. In: Handbook of Animal Models of Infection. Experimental Models in Antimicrobial Chemotherapy (Sande MA, eds) Academic Press, San Diego, pp 1069–1076.

  • Watowich SS, Liu KD, Xie X, Lai SY, Mikami A, Longmore GD, Goldsmith MA (1999) Oligomerization and scaffolding functions of the erythropoietin receptor cytoplasmic tail. J. Biol. Chem. 274:5415–5421.


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