Gladstone Home blank GIVI HOME
 
spacer
GIVI HOME

Gladstone Institutes Home  
Institute of
Cardiovascular Disease
GICD
 
Institute of
Neurological Disease
GIND
 
Center for
Translational
Research
CTR
University of California,
San Francisco
UCSF
 
Supporting Gladstone
Publications 2007
  • Abrams DI, Shade SB, Couey B, Couey P, McCune JM, Lo J, Bacchetti P, Chang B, Epling L, Liegler T, Grant RM (2007) Dehydroepiandrosterone (DHEA) effects on HIV replication and host immunity: A randomized placebo-controlled study. AIDS Res. Hum. Retroviruses 23:77–85.

  • Ahuja N, Schwer B, Carobbio S, Waltregny D, North BJ, Castronovo V, Maechler P, Verdin E (2007) Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase. J. Biol. Chem. 282:33583–33592.

  • Barrett A, Santangelo A, Tan K, Catchpole S, Roberts K, Spencer-Dene B, Hall D, Scibetta A, Burchell J, Verdin E, Freemont P, Taylor-Papadimitriou J (2007) Breast cancer associated transcriptional repressor PLU-1/JARID1B interacts directly with histone deacetylases. Int. J. Cancer 121:265–275.

  • Bisgrove DA, Mahmoudi T, Henklein P, Verdin E. Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription. Proc. Natl. Acad. Sci. USA 104:13690–13695.

  • Bourara K, Liegler TJ, Grant RM (2007) Target cell APOBEC3C can induce limited G-to-A mutation in HIV-1. PLoS Path. 3:1477–1485.

  • Cavrois M, Neidleman J, Kreisberg JF, Greene WC (2007) In vitro derived dendritic cells trans-infect CD4 T cells primarily with surface-bound HIV-1 virions. PLoS Path. 3:e4.

  • Chen L-f, Greene WC (2007) Regulation of nuclear NF-kB action: A key role for posttranslational modification. In: Handbook of Transcription Factor NF-kB (Ghosh S, ed.), CRC Press, Boca Raton, FL, pp. 87–105.

  • Colfax GN, Vittinghoff E, Grant R, Lum P, Spotts G, Hecht FM (2007) Frequent methamphetamine use is associated with primary non-nucleoside reverse transcriptase inhibitor resistance. AIDS 21:239–241.

  • de Noronha C, Greene WC (2007) Retroviruses and the Nucleus. In: Hiscox JA (Ed.), Viruses and the Nucleus, John Wiley & Sons, Ltd., Chicester, UK, pp. 89–128.

  • Ellery PJ, Tippett E, Chiu Y-L, Paukovics G, Cameron PU, Solomon A, Lewin SR, Gorry PR, Jaworowski A, Greene WC, Sonza S, Crowe SM (2007) The CD16+ monocyte subset is more permissive to infection and preferentially harbors HIV-1 in vivo. J. Immunol. 178:6581–6589.

  • Garrison KE, Jones RB, Meiklejohn DA, Anwar N, Ndhlovu LC, Chapman JM, Erickson AL, Agrawal A, Spotts G, Hecht FM, Rakoff-Nahoum S, Lenz J, Ostrowski MA, Nixon DF (2007) T cell responses to human endogenous retroviruses in HIV-1 infection. PLoS Path. 3:e165.

  • Goffinet C, Michel N, Allespach I, Tervo HM, Hermann V, Kraeusslich HG, Greene WC, Keppler OT (2007) Primary T-cells from human CD4/CCR5-transgenic rats support all early steps of HIV-1 replication including integration, but display impaired viral gene expression. Retrovirology 4:53.

  • Grant RM (2007) Research in situ. Nat. Methods 4:887–890.

  • Greene WC, Peterlin BM. Molecular biology of HIV: Implications for new therapies. In: Global HIV/AIDS Medicine (Sande M, Lange J, Volberding P, Greene WC, eds.), Elsevier, Philadelphia, 2007, pp. 23–38.

  • Greene WC (2007) A history of AIDS: Looking back to see ahead. Eur. J. Immunol. 37:S94–102.

  • Hetzer C, Bisgrove D, Cohen MS, Pedal A, Kaehlcke K, Speyerer A, Bartscherer K, Taunton J, Ott M (2007) Recruitment and activation of RSK2 by HIV-1 Tat. PLoS ONE 1:e151.

  • Karlsson AC, Iverson ASN, Chapman JM, de Oliveira T, Spotts G, McMichael AJ, Davenport MP, Hecht FM, Nixon DF (2007) Sequential broadening of CTL responses in early HIV-1 infection is associated with viral escape. PLoS One 2:e225.

  • Karlsson AC, Chapman JM, Heiken BD, Hoh R, Kallas EG, Martin JN, Hecht FM, Deeks SG, Nixon DF (2007) Antiretroviral drug therapy alters the profile of human immunodeficiency virus type 1-specific T-cell responses and shifts the immunodominant cytotoxic T-lymphocyte response from Gag to Pol. J. Virol. 81:11543–11548.

  • Kasler HG, Verdin E (2007) Histone deacetylase 7 functions as a key regulator of genes involved in both positive and negative selection of thymocytes. Mol. Cell. Biol. 27:5184–5200.

  • KrennHrubec K, Marshall BL, Hedglin M, Verdin E, Ulrich SM (2007) Design and evaluation of ‘linkerless’ hydroxamic acids as selective HDAC8 inhibitors. Bioorg. Med. Chem. Lett. 17:2874–2878.

  • Lombard DB, Alt FW, Cheng HL, Bunkenborg J, Streeper RS, Mostoslavsky R, Kim J, Yancopoulos G, Valenzuela D, Murphy A, Yang Y, Chen Y, Hirschey MD, Bronson RT, Haigis M, Guarente LP, Farese RV Jr., Weissman S, Verdin E, Schwer B (2007) Mammalian Sir2 homolog SIRT3 regulates global mitrochondrial lysine acetylation. Mol. Cell Biol. 27:8807–8814.

  • North BJ, Verdin E (2007) Mitotic regulation of SIRT2 by CDK1-dependent phosphorylation. J. Biol. Chem. 282:19546–19555.

  • North BJ, Verdin E (2007) Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis. PLoS One 2:e784.

  • Ohnuma-Ishikawa K, Morio T, Yamada T, Sugawara Y, Ono M, Nagasawa M, Yasuda A, Morimoto C, Ohnuma K, Dan NH, Hosoi H, Verdin E, Mizutani S (2007) Knockdown of XAB2 enhances all-trans retinoic acid-induced cellular differentiation in all-trans retinoic acid-sensitive and -resistant cancer cells. Cancer Res. 67:1019–1029.

  • Pagan JK, Arnold J, Hanchard KJ, Kumar R, Bruno T, Jones MJK, Richard DJ, Forrest A, Spurdle A, Verdin E, Crossley M, Faciulli M, Chenevix-Trench G, Young DB, Khanna KK (2007) A novel corepressor, BcoR-L1, represses transcription through an interaction with CtBP. J. Biol. Chem. 282:15248–15257.

  • Parra M, Mahmoudi T, Verdin E (2007) Myosin phosphatase dephosphorylates HDAC7, controls its nucleoplasmic shuttling, and inhibits apoptosis in thymocytes. Genes Dev. 21:638–643.

  • Petersen L, Taylor D, Roddy R, Belai G, Phillips P, Nanda K, Grant R, Clarke EE, Doh AS, Ridzon R, Jaffe HS, Cates W (2007) Tenofovir Disoproxil Fumarate for Prevention of HIV Infection in Women: A Phase 2, Double-Blind, Randomized, Placebo-Controlled Trial. PLoS Clin. Trials 2:e27.

  • Roan NR, Greene WC. A Seminal Finding for Understanding HIV Transmission. Cell 131:1044–1046.

  • Saunders LR, Verdin E (2007) Sirtuins: critical regulators at the crossroads between cancer and aging. Oncogene 26:5489–5504.

  • Soros VB, Yonemoto W, Greene WC (2007) Newly synthesized APOBEC3G is incorporated into HIV virions, inhibited by HIV RNA, and subsequently activated by RNase H. PLoS Path. 3:e15.

  • Stopak KS, Chiu Y-L, Kropp J, Grant RM, Greene WC (2007) Distinct patterns of cytokine regulation of APOBEC3G expression and activity in primary lymphocytes, macrophages, and dendritic cells. J. Biol. Chem. 282:3539–3546.

  • Verdin E (2007) AROuSing SIRT1: Identification of a novel endogenous SIRT1 activator. Mol. Cell 28:354–356.

  • Williams SA, Kwon H, Chen L-F, Greene WC (2007) Sustained induction of NF-kB is required for efficient expression of latent HIV-1. J. Virol. 81:6043–6056.

  • Williams SA, Greene WC (2007) Regulation of HIV-1 latency by T-cell activation. Cytokine 39:63–74.


Gladstone Home | Cardiovascular Disease | Virology and Immunology | Neurological Disease | Administration | UCSF