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Supporting Gladstone
Publications 2008
  • Burt TD, Agan BK, Marconi VC, He W, Kulkarni H, Mold JE, Cavrois M, Huang Y, Mahley RM, Dolan MJ, McCune JM, Ahuja SK (2008) Apolipoprotein (apo) E4 enhances HIV-1 cell entry in vitro, and the APOE ε4/ε4 genotype accelerates HIV disease progression. Proc. Natl. Acad. Sci. USA 105:8718–8723.

  • Cavrois M, Neidleman J, Greene WC (2008) The achilles heel of the Trojan horse model of HIV trans-infection. PLoS Pathog. 4:e1000051.

  • Chiu Y-L, Greene WC (2008) The APOBEC3 cytidine deaminases: An innate defensive network opposing exogenous retroviruses and endogenous retroelements. Ann. Rev. Immunol. 26:317–353.

  • Chiu Y-L, Greene WC. APOBEC3G: An intracellular centurion. Phil. Trans. R. Soc. B. In press.

  • Fauci AS, Johnston MI, Dieffenbach CW, Burton DR, Hammer SM, Hoxie J, Martin M, Overbaugh J, Watkins DI, Mahmoud A, Greene WC (2008) HIV Vaccine Research: The Way Forward. Science 321:530–532.

  • Grant RM. Antiretroviral treatment in recently infected persons. In: Approach towards management of HIV infection and its related complications (V. Yu, ed.) Lippincott, Williams and Wilkins, Hagerstown, MD, In Press.

  • Grant RM, Hamer D, Hope T, Johnston R, Lange J, Lederman MM, Lieberman J, Miller CJ, Moore JP, Mosier DE, Richman DD, Schooley RT, Springer MS, Veazey RS, Wainberg MA (2008) Whither or wither microbicides? Science 321:532–534.

  • Kwon H-S, Brent MM, Getachew R, Jayakumar P, Chen L-F, Schnolzer M, McBurney MW, Marmorstein R, Greene WC, Ott M (2008) Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation. Cell Host Microbe 3:158–167.

  • Lee AW, Sharp ER, O'Mahony A, Rosenberg MG, Israelski DM, Nolan GP, Nixon DF (2008) Single-cell, phosphoepitope-specific analysis demonstrates cell type- and pathway-specific dysregualtion of Jak/STAT and MAPK signaling associated with in vivo human immunodeficiency virus type 1 infection. J. Virol. 82:3702–3712.

  • McLaughlin BE, Baumgarth N, Bigos M, Roederer M, De Rosa SC, Altman JD, Nixon DF, Ottinger J, Li J, Beckett L, Shacklett BL, Evans TG, Asmuth DM (2008) Nine-color flow cytometry for accurate measurement of T cell subsets and cytokine responses. Part II: Panel performance across different instrument platforms. Cytometry A 73:411–420.

  • McLaughlin BE, Baumgarth N, Bigos M, Roederer M, De Rosa SC, Altman JD, Nixon DF, Ottinger J, Oxford C, Evans TG, Asmuth DM (2008) Nine-color flow cytometry for accurate measurement of T cell subsets and cytokine responses. Part I: Panel design by an empiric approach. Cytometry A 73:400–410.

  • Napolitano LA, Schmidt D, Gotway M, Ameli N, Filbert EL, Ng MN, Clor JL, Epling L, Sinclair E, Li K, Baum P, Killian ML, Bacchetti P, McCune JM (2008) Growth Hormone Enhances Thymic Function in HIV-infected Adults. J. Clin. Invest. 118:1085–1098.

  • Neugebauer RC, Uchiechowska U, Meier R, Hruby H, Valkov V, Verdin E, Sippi W, Jung M (2008) Structure-activity studies on splitomicin derivatives as sirtuin inhibitors and computational prediction of binding mode. J. Med. Chem. 51:1203–1213.

  • Santiago ML, Greene WC (2008) The role of the APOBEC3 family of cytidine deaminases in innate immunity, G-to-A hypermutation, and evolution of retroviruses. In: Origin and Evolution of Viruses (E. Domingo, C. Parrish, J.L. Holland, eds.) Elsevier Publishers, Boston, MA, pp. 183–205.

  • Santiago ML, Montano M, Benitez R, Messer RJ, Yonemoto W, Chesebro B, Hasenkrug KJ, Greene WC (2008) APOBEC3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection. Science 321:1343–1346. DOI: 10.1126/science.1161121

  • Schafer S, Saunders L, Eliseeva E, Velena A, Jung M, Schwienhorst A, Strasser A, Diskmanns A, Ficner R, Schlimme S, Sippl W, Verdin E, Jung M (2008) Phenylalanine-containing hydroxamic acids as selective inhibitors of class IIb histone deacetylases (HDACs). Bioorg. Med. Chem. 16:2011–2033.

  • Schwer B, Verdin E (2008) Conserved metabolic regulatory functions of sirtuins. Cell Metab. 7:104–112.

  • Scott G, Marx C, Berger C, Saunders L, Verdin E, Schafer S, Jung M, Benz C (2008) Destabilization of ERBB2 transcript by targeting 3' UTR mRNA-associated HuR and histone deacetylase-6 (HDAC6). Mol. Cancer Res. 6:1250–1258.

  • Strickler HD, Fazzari M, Kovacs A, Isasi C, Napolitano LA, Minkoff H, Gange S, Young M, Sharp GB, Kaplan RC, Cohen M, Gunter MJ, Harris TG, Yu H, Schoenbaum E, Landay AL, Anastos K (2008) Associations of Insulin-Like Growth Factor-1 (IGF-1) and IGF Binding Protein-3 with HIV Disease Progression in Women. J. Inf. Dis. 197:319–327.

  • Wang S, Li X, Parra M, Verdin E, Bassel-Duby R, Olson EN (2008) Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7. Proc. Natl. Acad. Sci. USA 105:7738–7743.


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