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Publications 2000
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- Berkowitz RD, Alexander S, McCune JM (2000) Causal relationships between HIV-1 coreceptor utilization, tropism, and pathogenesis in human thymus. AIDS Res. Hum. Retroviruses 16:1039–1045.
- Blower SM, Gershengorn HB, Grant RM (2000) A tale of two futures: HIV and antiretroviral therapy in San Francisco. Science 287:650–654.
- Chan SY, Ma MC, Goldsmith MA (2000) Differential
induction of cellular detachment by envelope glycoproteins of Marburg and Ebola (Zaire) viruses. J. Gen. Virol.
81:2155–2159.
- Chan SY, Speck RF, Ma MC, Goldsmith MA (2000) Distinct mechanisms of entry by envelope glycoproteins of Marburg and Ebola (Zaire) viruses. J. Virol. 74:4933–4937.
- Deeks SG, Barbour JD, Martin JN, Swanson MS, Grant RM (2000) Sustained CD4+ T cell response after virologic failure of protease inhibitor–based regimens in patients with human immunodeficiency virus infection. J. Infect. Dis. 181:946–953.
- Esser U, Speck RF, Deen KC, Atchison RE, Sweet R,
Goldsmith MA (2000) Molecular function of the CD4 D1 domain in coreceptor-mediated entry by HIV type 1. AIDS Res. Hum. Retroviruses 16:1845–1854.
- Foehr ED, Bohuslav J, Chen L-F, DeNoronha C, Geleziunas R, Lin X, O'Mahony A, Greene WC (2000) The NF-kB-inducing kinase induces PC12 cell differentiation and prevents apoptosis. J. Biol. Chem. 275:34021–34024.
- Foehr ED, Lin X, O'Mahony A, Geleziunas R, Bradshaw RA, Greene WC (2000) NF-kB signaling promotes both cell survival and neurite process formation in nerve growth factor-stimulated PC12 cells. J.
Neurosci. 20:7556–7563.
- Gobbi A, Stoddart CA, Locatelli G, Santoro F, Bare C,
Linquist-Stepps V, Moreno ME, Abbey NW, Herndier BG, Malnati MS, McCune JM, Lusso P (2000) Coinfection of SCID-hu Thy/Liv mice with human herpesvirus 6 and human immunodeficiency virus type 1. J. Virol. 74:8726–8731.
- Greenblatt RM, Ameli N, Grant RM, Bacchetti P, Taylor RN (2000) Impact of the ovulatory cycle on virologic and immunologic markers in HIV-infected women. J. Infect. Dis. 181:82–90.
- Grivel J-C, Penn ML, Eckstein DA, Schramm B, Speck RF, Abbey NW, Herndier B, Margolis L, Goldsmith MA (2000) Human immunodeficiency virus type 1 coreceptor preferences determine target T-cell depletion and cellular tropism in human lymphoid tissue. J. Virol. 74:5347–5351.
- Guenther MG, Lane WS, Fischle W, Verdin E, Lazar MA,
Shiekhattar R (2000) A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness. Genes Dev. 14:1048–1057.
- Henklein P, Bruns K, Sherman MP, Tessmer U, Licha K, Kopp J, de Noronha C, Greene WC, Wray V, Schubert U (2000) Functional and structural characterization of synthetic HIV-1 Vpr that transduces cells, localizes to the nucleus, and induces G2 cell cycle arrest. J. Biol. Chem. 275:32016–32026.
- Huang SS, Barbour JD, Deeks SG, Huang JS, Grant RM, Ng VL, McCune JM (2000) Reversal of human immunodeficiency virus type 1–associated hematosuppression by effective antiretroviral therapy. Clin. Infect. Dis. 30:504–510.
- Huynh KD, Fischle W, Verdin E, Bardwell VJ (2000) BCoR, a novel corepressor involved in BCL-6 repression. Genes Dev. 14:1810–1823.
- Jenkins M, Keir M, McCune JM (2000) A membrane-bound Fas decoy receptor expressed by human thymocytes. J. Biol. Chem. 275:7988–7993.
- Kruhlak MJ, Lever MA, Fischle W, Verdin E, Bazett-Jones DP, Hendzel MJ (2000) Reduced mobility of the alternate splicing factor (ASF) through the nucleoplasm and steady state speckle compartments. J. Cell Biol. 150:41–51.
- Lin L, DeMartino GN, Greene WC (2000) Cotranslational dimerization of the Rel homology domain of NF-kB1 generates p50–p105 heterodimers and is required for effective p50 production. EMBO J. 19:4712–4722.
- Lin X, O'Mahony A, Mu Y, Geleziunas R, Greene WC (2000) Protein kinase C-q participates in NF-kB activation induced by CD3-CD28 costimulation through selective activation of IkB kinase b. Mol. Cell. Biol. 20:2933–2940.
- Locher CP, Grant RM, Collisson EA, Reyes-Terán G, Elbeik T, Kahn JO, Levy JA (2000) Antibody and cellular immune responses in breakthrough infection subjects after HIV type 1 glycoprotein 120 vaccination.
AIDS Res. Hum. Retroviruses 15:1685–1689.
- McCune JM, Hanley MB, Cesar D, Halvorsen R, Hoh R,
Schmidt D, Wieder E, Deeks S, Siler S, Neese R, Hellerstein M (2000) Factors influencing T-cell turnover in HIV-1–seropositive patients. J. Clin. Invest. 105:R1–R8.
- McKenzie FR, Connelly MA, Balzarano D, Müller JR, Geleziunas R, Marcu KB (2000) Functional isoforms of IkB kinase a (IKKa) lacking leucine zipper and helix-loop-helix domains reveal that IKKa and IKKb have different activation requirements. Mol. Cell. Biol. 20:2635–2649.
- Mori N, Ueda A, Ikeda S, Yamasaki Y, Yamada Y, Tomonaga M, Morikawa S, Geleziunas R, Yoshimura T, Yamamoto N (2000) Human T-cell leukemia virus type I Tax activates transcription of the human monocyte chemoattractant protein-1 gene through two nuclear factor-kB sites. Cancer Res. 60:4939–4945.
- Moss NE, Lemp G, Bluthenthal R, Goldsmith MA, Haubrich R, Kahn JO (2000) From the cell to the community: AIDS research in California. The University of California Universitywide AIDS Research Program annual meeting, February 2000. West. J. Med. 173:119–124.
- O'Mahony A, Lin X, Geleziunas R, Greene WC (2000) Activation of the heterodimeric IkB kinase a (IKKa)-IKKb complex is directional: IKKa regulates IKKb under both basal and stimulated conditions. Mol. Cell. Biol. 20:1170–1178.
- Schlegel P, Beatty P, Halvorsen R, McCune J (2000)
Successful allogeneic bone marrow transplant in an HIV-1–positive man with chronic myelogenous leukemia. J. Acquir. Immune Defic. Syndr. 24:289–290.
- Schramm B, Penn ML, Palacios EH, Grant RM, Kirchhoff F, Goldsmith MA (2000) Cytopathicity of human immunodeficiency virus type 2 (HIV-2) in human lymphoid tissue is coreceptor dependent and comparable to that of HIV-1. J. Virol. 74:9594–9600.
- Schramm B, Penn ML, Speck RF, Chan SY, De Clercq E, Schols D, Connor RI, Goldsmith MA (2000) Viral entry through CXCR4 is a pathogenic factor and therapeutic target in human immunodeficiency virus type 1 disease. J. Virol. 74:184–192.
- Sherman MP, de Noronha CMC, Pearce D, Greene WC (2000) Human immunodeficiency virus type 1 Vpr contains two leucine-rich helices that mediate glucocorticoid receptor coactivation independently of its effects on G2 cell cycle arrest. J. Virol. 74:8159–8165.
- Smith KY, Valdez H, Spritzler J, Kessler HA, Connick E,
Kuritzkes D, Gross B, Francis I, McCune JM, Lederman MM, ACTG 375 Protocol Team (2000) Thymic size and lymphocyte restoration in patients with human
immunodeficiency virus infection after 48 weeks with zidovudine, lamivudine, and ritonavir therapy. J. Infect. Dis. 181:141–147.
- Stoddart CA, Moreno ME, Linquist-Stepps VD, Bare C, Bogan MR, Gobbi A, Buckheit RW, Jr., Bedard J, Rando RF, McCune JM (2000) Antiviral activity of 2'-deoxy-3'-oxa-4'-thiocytidine (BCH-10652) against lamivudine-resistant human immunodeficiency virus type 1 in SCID-hu Thy/Liv mice. Antimicrob. Agents Chemother. 44:783–786.
- Wang J-K, Kiyokawa E, Verdin E, Trono D (2000) The Nef protein of HIV-1 associates with rafts and primes T cells for activation. Proc. Natl. Acad. Sci. USA 97:394–399.
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