Focus: Studies of the molecular basis for HIV pathogenesis, transmission, and latency and the biochemical mechanisms underlying the regulation and action of the NF-κB/Rel family of eukaryotic transcription factors.

Focus: Studies of HIV genetic diversity, the causes and consequences of drug failure in HIV infection, optimization of antiretroviral therapy based on assessment of viral genotype and phenotype, studies of HIV superinfection, and assessment of HIV replication/latency in different tissue sanctuaries.

Focus: Structure and function of viral genome organization. Gene regulation during latency of the Epstein-Barr virus, Kaposi's sarcoma-associated herpesvirus, human immunodeficiency virus, and human papillomavirus

Focus: Molecular mechanisms of HIV-1 Tat function, including its reversible acetylation; biology of hepatitis C virus infection with a focus on the core protein.

Focus: To understand how pro– and anti–inflammatory cytokines control the adaptive immune response against acute and chronic pathogenic infections; in particular, the interplay between TGFβ signaling and the common gamma chain cytokines (i.e. IL-2, IL-7, and IL-15) in T cell differentiation, function, and survival.

Focus: Mechanism by which HIV establishes viral latency, characterization of natural Tat-inhibitory factors, and the biochemistry and function of class 1,2, and 3 histone deacetylases in normal cell biology.