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World AIDS Day Outreach
World AIDS Day, December 1, is one of the most recognized international health days and a key opportunity to raise further awareness in communities and across the world about the state of the pandemic and critical next steps that must be taken to halt its spread.

On World AIDS Day 2008, scientists from the Gladstone Institute of Virology and Immunology marked the day with visits to local schools and presented students with information on AIDS and HIV. The presenters who spoke to high school classes discussed HIV prevention, described HIV research that is taking place at Gladstone, and briefly described their own career paths in science. They ended with some exciting science directly out of their own lab books.

Those who presented to elementary school students tailored their presentations appropriately. The elementary school students displayed a lot of creativity with a “draw me a virus” exercise and also learned how to dress in protective biosafety gowns.

The visited schools included Junipero Serra Elementary School, Philip & Sara Burton Academic High School, and John O’Connell High School of Technology. Gladstone has established a relationship with these local schools through its Community Student Outreach Committee and has been fortunate to work with very committed administrators and teachers with a shared goal of inspiring future scientists and research staff by promoting science education and scientific careers for students in our community.

Scientists from GIVI who participated included postdoctoral fellows Eva Herker, Andrew Hebbeler, David Lim, Aaron Middlebrook, Sara Pagans-Lista, Satish Pillai, Sara Pagans, Mario Santiago; graduate students Nicole Byers and Leonard Chavez; research associate Patricia Defechereux; and associate investigator Melanie Ott. Laura Saunders, a research scientist in the Verdin Laboratory, also played a key role in organizing this event.

"On December 1, 2008, Eva, Patricia, Melanie, and I went to the Junipero Serra Elementary School in Bernal Heights to give a class about HIV and AIDS. Mine was a 4th grade class, and their teacher was Joy Larkin. I explained to them that there are different viruses, and one of them is HIV, which causes a disease called AIDS. They understood very well that the virus defeats our “army” of white blood cells, and they really liked playing a game with a ball (which represented the virus).

Then, I dressed a student as a scientist with gown, goggles, and blue gloves, and gave her some eppendorf tubes and falcons. Finally, before they left, the teacher asked them to write what they learned during the hour-long class, and these are some examples of what they wrote." Sara Pagans-Lista, PhD, Ott Lab


"On Monday, December 15, 2008, I had the opportunity and the good fortune to visit John O’Connell High School in the mission district. I spoke to a combined group of about 45 students that ranged in age from about 15 to 17 years old. Half of the group was from an 11th grade chemistry class and the other half from a 10th grade biology class. The entire group gave me their undivided attention throughout my presentation, which included an overview of the AIDS pandemic’s history and present status, HIV pathology and clinical course, an explanation of how my work fits into the fight against the virus and most importantly how they can protect themselves. They were very taken by the fact that they possessed an organ (the thymus) that produced T cells and that this organ lost the majority of its function at a relatively early age. There was an excellent question regarding HIV transmission by a mosquito. Mosquitoes do not actually inject any blood from previous victims when they bite you, instead they inject saliva which acts as a lubricant to facilitate feeding. Malaria is, however, a disease that is transmitted via the saliva of mosquitos.

All-in-all this was an extremely positive experience. I came away invigorated by the feeling that my work is important and relevant to the community at large, not just to my scientific colleagues. I very much appreciated this opportunity." Aaron Middlebrook, PhD, Napolitano lab


"I visited a 9th grade class at Burton High School and gave a presentation first describing the global and local impact of HIV and AIDS. I discussed how this disease continues to afflict a broad range of individuals from large African populations of young mothers, fathers, and children to everyday, local San Francisco community members such as police officers, firefighters, doctors, lawyers, and many others.

I next described how HIV infects and kills CD4 cells, the sergeant-master of our immune system and that loss of CD4 cells opens the window for bacteria, fungi, and other viruses to infect patients. The students were very curious why HIV chose CD4 cells as its target and one student remarked, “If you’re losing so many CD4 cells, why don’t you just transfuse HIV-resistant CD4 cells back into patients?” It was very clear to me the class was engaged, thinking, and trying to invent solutions to the proposed problems. My discussion sparked a creative discussion that was marked with a youthful, energetic curiosity that reminded me of some of my first science classes in high school. Commemorating World AIDS Day 2008 at Burton High School re-emphasized to me the importance of always engaging our youth in science through open, fun, but precise discussion about the problems and challenges that face the medical and scientific fields today. I am honored to have been a part of AIDS Outreach 2008 and hope that I may have sparked even just one student’s enjoyment of science even if only for a day." David Lim, MD, PhD, Greene lab



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