December 1, 2006
Director of the Gladstone Institute of Virology and Immunology, Dr Warner Greene, and President of the Gladstone Institutes, Dr Robert Mahley are featured in this CBS news report on World AIDs Day 2006
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On brink of Alzheimer's breakthrough
By Joseph Hall
Toronto Star, November 17, 2006
You can see him struggle as he tries to recall his children and grandchildren, counting along the fingers of his left hand.
“There's Robin, yes, and Andrew,” he says, slowly assigning each a different digit. “And grandchildren, let's see. There's Reilly and ... and ... a whole list of them.”
At one time, it would have been a foregone conclusion that Scott Millar would lose the names of his loved ones due to the ravages of Alzheimer's, the brain–wasting ailment German neurologist Alois Alzheimer first described a 100 years ago this month.... MORE
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Alzheimer's research makes dramatic shift
By Sharon Begley
Pittsburgh Post-Gazette, from The Wall Street Journal, November 17, 2006
For any normal field of science, the conclusion that “there is more to (fill in a disease) than (fill in leading but unproved hypothesis) alone” wouldn't cause anyone to bat an eye. After all, science is supposed to consider all reasonable ideas. But Alzheimer's disease is not your normal field of science... MORE
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Gladstone and Merck team to bring drugs to market
By Daniel S. Levine
San Francisco Business Times, November 10, 2006
The J. David Gladstone Institutes and drug giant Merck & Co. have struck a deal that will launch a new effort by the institutes to see its discoveries turned into commercial therapies... MORE
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Gladstone Institutes Honor Debas, Smith with Trustee Awards
By Valerie Tucker
UCSF Today, September 13, 2006
The J. David Gladstone Institutes honored Haile T. Debas, MD, and Lloyd H. “Holly” Smith, MD, for their instrumental roles developing the UCSF-affiliated research institutes... MORE
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Post-docs start getting respect at research units
By Kristen Bole
San Francisco Business Times, September 1, 2006
Last year, the J. David Gladstone Institutes ranked 12th on the Scientist magazine's list of best places for post-doctoral fellows to work. It wasn't good enough... MORE
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Shorenstein has biotech FibroGen on hook for Mission Bay
By J.K. Dineen
San Francisco Business Times, August 4, 2006
South San Francisco-based FibroGen has signed a letter of intent to lease more than half of the 450,000-square-foot waterfront life science complex Shorenstein Properties is preparing to build in Mission Bay... MORE
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Dr. Mahley interviewed for stem cell therapy story
By John Fowler
KTVU-TV, July 26, 2006
Dr. Robert W. Mahley is interviewed as part of a story about a Palo Alto man who traveled to Thailand for a stem cell transplant to treat a damaged heart... MORE
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Double Positive:
People who already have HIV brace for a second assault
By Josh Sparber
POZ, August, 2006
Back when HIV was identified,in 1983, scientists theorized that superinfection—-contracting a second HIV strain after initial infection—-was likely. Their fear: A second strain could complicate treatment and spur HIV progression. Only 21 apparent superinfection cases have been charted since 2002, however, so health experts might have cried wolf without explaining who, precisely, should fear the beast... MORE
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Analysis:
Stem-cell therapies advance
 By Steve Mitchell
UPI, June 28, 2006
Experts said Wednesday scientists are making progress in the potential to use both embryonic and adult stem cells to treat heart disease, and clinical applications are expected soon... MORE
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Science Pen Pals
By Ishani Ganguli
The Scientist, June, 2006
Last spring, Sue Saunders was writing a grant proposal for the elementary school where she runs an after-school literacy program when a conversation with her daughter, Laura, a postdoc studying cancer biology at the J. David Gladstone Institutes, gave her an idea... MORE
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Can You Go Home Again?
By Karen Pallarito
The Scientist, June, 2006
Going from academia to business—and back again—is no easy feat. The exceptions not only prove the rule, but also that it can be done... MORE
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Gladstone Public Lecture:
“Stem Cell Biology 101: An Introduction to the Science and the Politics”
By Sharon Brock
UCSF Today, June 19, 2006
The science and politics of stem cell research were presented last week by Deepak Srivastava, director of the Gladstone Institute of Cardiovascular Disease, and David L. Gollaher, president and CEO of the California Healthcare Institute, as a part of Gladstone's Science for Life lecture series... MORE
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AIDS at 25
By Thomas H. Maugh II and Jia-Rui Chong
Los Angeles Times, June 5, 2006
A quarter-century after the beginning of the AIDS epidemic, the rapid pace of scientific discovery has slowed to a crawl. The early years of the epidemic were a sprint, as researchers isolated the virus that causes AIDS, developed rapid tests for the virus and found drugs that could block its replication... MORE
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Is VoIP Simplifying Life For Small and Medium-Sized Enterprises?
By Christian Perry
Processor.com, June 1, 2006
Touted heavily by vendors as the smart choice for companies looking to implement new or replacement phone equipment, VoIP appears poised to carve major inroads into the enterprise communication landscape. But seeing through the mountains of hype surrounding VoIP can be difficult... MORE
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Mahley dares MC graduates to live fully
By Karen B. Eldridge
Maryville College News, May 22, 2006
Dare to embrace a compelling theme for your life and dare to rise above failures, setbacks and shortcomings.
This was the advice to Maryville College's Class of 2006 from Dr. Robert Mahley... MORE
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Stem cell fellows:
Demand outstrips supply at key institutions
By Daniel S. Levine
San Francisco Business Times, May 19, 2006
Demand for fellowships funded by the California Institute for Regenerative Medicine's training grants are far outstripping available spaces, according to Bay Area institutions awarded funding... MORE
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Studies Bloom on Alzheimer's as Boomers Age
By Erin Allday
San Francisco Chronicle, May 15, 2006
The long race to develop a cure, or even a viable treatment, for Alzheimer's disease is quickly turning into a sprint as the Baby Boomer generation heads toward old age... MORE
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New drug combination to be tested in people for preventing AIDS infection
By Steve Johnson
San Jose Mercury News, May 11, 2006
A drug made by Gilead Sciences of Foster City showed so much promise protecting monkeys from getting the AIDS virus that scientists want to test it in people in at least three countries to see if it can help slow the global AIDS epidemic... MORE
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Few Health Officials Ready to Promote Serosorting
By Matthew S. Bajko
Bay Area Reporter, May 4, 2006
The trend of gay men choosing to have sex with men of the same HIV status is universally credited with helping to bring about falling rates of HIV infections in San Francisco. But the practice, known as serosorting, has yet to receive an official stamp of approval... MORE
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New Alzheimer's theory:
Glucose metabolism drug used for diabetics shows ability to thwart damaging changes in key parts of brain cells
By Jamie Talan
Newsday, May 3, 2006
A diabetes drug used to regulate glucose metabolism may work in treating Alzheimer’s, according to a new study. The theory suggests that drugs used to regulate the body's own insulin may prevent the mind-robbing disease. "This opens a new avenue for the treatment for Alzheimer’s," said Dr. Yadong Huang, an investigator at the Gladstone Institutes... MORE
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Can Drugs Prevent HIV?
Center Forum Explores Studies Aimed at Testing Pre-Infection Interventions
By Duncan Osborne
Gay City News (New York), April 27, 2006
A forum held at the Lesbian, Gay, Bisexual and Transgender Community Center explored the current studies and future potential of using anti-HIV drugs to keep HIV-negative people from becoming infected with the virus that causes AIDS... MORE
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Two UCSF Scientists Elected to American Academy of Arts and Sciences
UCSF Today, April 24, 2006
Two UCSF faculty scientists have been elected to the American Academy of Arts and Sciences, the academy announced today. Jeffrey A. Bluestone, PhD, director of the UCSF Diabetes Center, and Robert W. Mahley, MD, PhD, president of the UCSF-affiliated J. David Gladstone Institutes, were among 175 new fellows elected to the academy... MORE
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Profile of Robert W. Mahley
By Regina Nuzzo
Proceedings of the National Academy of Science, April 11, 2006
Heart disease and the church were two forces that shaped the teenage years of cardiovascular biologist Robert W. Mahley. The first, in the form of a massive heart attack, stole his 37-year-old father... MORE [PDF 157k]
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Windows on Macs, Oh My!
By Charles Babcock
InformationWeek, April 10, 2006
Apple last week offered free software called Boot Camp that lets users run Windows XP on its new Intel-based Macintoshes. It was only a matter of time before someone did... MORE
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Best Places to Work for Postdocs
By Ted Agres
The Scientist, March 1, 2006
The J. David Gladstone Institutes in San Francisco pays close attention to its postdocs' needs. John LeViathan, postdoc adviser and human resources manager, says Gladstone follows National Postdoctoral Association guidelines, offering excellent salaries and employee benefits, emphasizing mentoring... MORE [PDF 388k]
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Dating Within the HIV-Positive or Negative Population Has Reduced the HIV Infection Rate
By Christopher Heredia
San Francisco Chronicle Sunday Magazine, February 12, 2006
San Francisco lovers James Nykolay and Brian Basinger met in 2002 at the testosterone clinic at San Francisco General Hospital Medical Center's Ward 86. Both long-term HIV survivors, the men had appointments every Friday for treatment for AIDS-related wasting... MORE
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Two Promising New AIDS Drugs: Strong Results in Studies
By Sabin Russell
San Francisco Chronicle, February 9, 2006
Prospects for a new class of effective AIDS medicines soared Wednesday when two drugmakers reported surprisingly strong results from clinical trials of their experimental pills. The drugs, known as integrase inhibitors, performed as well or better than most of the antiviral medicines that serve as the mainstays of current therapies... MORE
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Editorial: Bringing Biotech Within Reach
The Examiner, January 20, 2006
San Francisco is poised for what could be a major increase in biotechnology businesses, and not just in the new Mission Bay neighborhood where the state's stem cell institute is headquartered... MORE [PDF]
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Wine Therapy
By Emily Hager
ScienCentral.com, December 15, 2005
Making a toast to your health could have new meaning this holiday season. Researchers have identified a substance in red wine that may help prevent Alzheimer's disease... MORE
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Super-Hyped Infection
By Cristi Hegranes
SF Weekly, December 14, 2005
At 2 a.m. on an unusually warm Saturday in November, Hadley sat in the back of a taxi, his head leaning on the windowpane. He was sobbing. It was an anniversary of sorts: it had been one year since he had tested positive... MORE
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Scientists find clue to battle brain disease
By Jennifer Gollan
Marin Independent Journal, November 29, 2005
In a promising step toward combating a fatal brain disease, scientists at the Buck Institute for Age Research in Novato have found that mice injected with a growth-promoting protein improved their brain function and lifespan. “The results look really exciting,” said Dr. Steven Finkbeiner, an associate investigator at the Gladstone Institute of Neurological Disease... MORE
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Academics Say S.F. Institutions Are Top-Notch: Gladstone, UCSF among Top 15 Places to Work
By Marisa Lagos
The Examiner, November 7, 2005
Scientific academics seem to have figured out what many San Franciscans have known for years: The City is a great place to work. The Gladstone Institutes and UCSF are two of the best places to work in academia, according to an annual survey by The Scientist that is being published today. Gladstone Institutes was rated third on the list... MORE [PDF 3.25mb]
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Starting from Scratch
By Reginald L. Drakeford, Sr., IT Officer, Gladstone Institutes
Scientific Computing & Instrumentation, October, 2005
With a new research facility, the Gladstone Institutes seized the opportunity to plan scientific computing solutions from the ground up... MORE
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City Students Receive Free Peek at Medical Field
By Bonnie Eslinger
The Examiner, October 3, 2005
Facing a critical shortfall in the number of students interested in going into the sciences, one Mission Bay biomedical center is working to send San Francisco high school students to an 11-day medical program at the University of California, Berkeley—for free. This year, nine students were chosen by the Gladstone Institutes... MORE [PDF 2.8mb]
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Bruce Conklin, MD, talks about CIRM training grant and Exploratorium stem cell exhibit
By Marc Strassman
Etopia Media Medical News Network, September 15, 2005
Bruce Conklin of the Gladstone Institute of Cardiovascular Disease is featured in a half-hour streaming audio interview discussing both a $2.4 million grant from the California Institute for Regenerative Medicine and Gladstone's involvement with a stem cell exhibit at the Exploratorium... MORE
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A Good Report on AIDS, and Some Credit the Web
By Dean E. Murphy
The Boston Globe, from The New York Times, August 17, 2005
The conversation over tossed salad, dinner rolls and iced tea was about dating. Mostly predictable stuff, like where to meet guys and the hottest men-seeking-men Web sites. But the gathering last week at a coffee shop in the largely gay Castro district was not a casual pick-up session. The dozen or so men were infected with the virus that causes AIDS... MORE |
Metropolitan Wires J. David Gladstone Institutes
The Voice, Summer, 2005
Metropolitan Electrical Construction of San Francisco has installed over one million feet of telecommunications cable at Mission Bay's first private biotech research laboratory, the J. David Gladstone Institutes... MORE
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S.F. Doctors Research Promising AIDS Strategy
By Bonnie Eslinger
The Examiner, August 14, 2005
Doctors working within San Francisco's budding biotech corridor are researching a new HIV treatment that helps find and eliminate hidden infected cells—a possible step in curing the deadly infection. Researchers at Mission Bay's Gladstone Institutes are using novel drugs to wake up dormant HIV cells that appear invisible... MORE [PDF 163k]
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San Francisco Researchers Report HIV Breakthrough
KRON-TV, August 12, 2005
Researchers are announcing a possible breakthrough in the fight against HIV. A new therapy now undergoing research in a San Francisco lab could hold out the possibility of an eventual cure... MORE |
KNTV Report
NBC Channel 11, San Francisco, August 11, 2005
A KNTV news report dealing with HIV/AIDS latency issues, featuring an interview with Eric Verdin. This report was distributed nationally and aired on more than 40 NBC affiliate stations around the country. |
HIV Treatment Raises Cure Hopes
By Emma Ross
Wired News, from the Associated Press, August 11, 2005
A new treatment strategy has shown promise in helping to transform HIV into a curable infection. Preliminary research published this week in The Lancet outlines how scientists used an anti-convulsant drug to awaken dormant HIV hiding in the body, where it is temporarily invisible but still dangerous... MORE |
KCBS-AM Interview about HIV Latency
August 11, 2005
Dr. Eric Verdin discusses a novel approach to dealing with dormant HIV lying hidden within cells. |
The Real Facts behind the HIV 'Superbug' and How Resistant
Strains Fit in to the Existing AIDS Epidemic
By Kerri Penno
ADVANCE for Medical Laboratory Professionals, July 11, 2005
The AIDS epidemic, both abroad and in the United States, shows no signs of slowing down. In fact, two decades after the virus first emerged, approximately 40,000 Americans are newly infected with HIV each year... MORE |
Science Project
By Will Crain
San Francisco Chronicle, July 10, 2005
Chris McKay is speaking about one of the moons of Saturn when he holds up what he says is a NASA-approved scale model of the distant satellite. In reality, it's a lemon. This is not exactly the Nobel Prize lecture in Oslo... MORE |
RNA Guides Differentiation:
Research Hints at How Stem Cells Specialize--or Avoid Specializing
By Sue Goetinck Ambrose
The Dallas Morning News, June 18, 2005
Proper development of the heart depends on tiny, once-overlooked snippets of the genetic molecule RNA, research from a Dallas lab suggests. The findings, reported this week, may help scientists solve a fundamental mystery in biology: how organs develop on time and to the proper size... MORE |
IT Directs Gladstone Design
By Salvatore Salamone
Bio-IT World, June, 2005
When the new six-story home of the J. David Gladstone Institutes recently won an award for its design, at least part of the credit showered on its architects should have been shared by Gladstone's information technology officer, Reginald “Reg” Drakeford, and many of Gladstone's researchers. Involving IT early in building design is a rare occurrence... MORE |
Smart Scopes Make Sense of Cellular Structures
By Gina Shaw
Drug Discovery & Development, May, 2005
At the Gladstone Institute of Neurological Disease, Steven Finkbeiner, MD, PhD, was trying to find an answer to a long-standing question in Huntington's disease research: what do the inclusion bodies of mutated Huntington protein that form in neuronal cells of people with the disease signify?... MORE |
May 24, 2005
A report that aired on “One Life,” a KMTP-TV (local channel 32) series dealing with HIV/AIDS issues, featuring an interview with Melanie Ott discussing HIV and hepatitis |
Will S.F.'s job plan be big box-office?
By Ken Garcia
San Francisco Chronicle, May 13, 2005
San Francisco tourism officials may always want to lure visitors with shots of cable cars climbing halfway to the stars, but business recruiters see the city's future riding on a decidedly different vehicle. This one is fueled by innovation, research, investment and hope... MORE |
Chimeras exist, what if some turn out too human?
By Sharon Begley
Pittsburgh Post-Gazette, from The Wall Street Journal, May 6, 2005
If you had just created a mouse with human brain cells, one thing you wouldn't want to hear the little guy say is, 'Hi there, I'm Mickey.' Even worse, of course, would be something like, 'Get me out of this body!'... MORE |
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AIDS and the secret of long-term survivors
By Carol Pogash
International Herald Tribune, May 5, 2005, from The New York Times, May 2, 2005
Before powerful antiviral medicines became available, Kai Brothers lost his partner and many friends to AIDS. Thinking he was next, he quit his job, emptied his retirement fund and waited to die... MORE
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Stem cell HQ pitch enters home stretch
Site visit gives city chance to sway selection group
By Marisa Lagos
The Examiner, April 29, 2005
Today will make or break San Francisco's bid to host the California Institute of Regenerative Medicine, when board members from the new stem cell agency arrive in The City to tour the proposed site... MORE [PDF 2.3mb]
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HIV-Resistant Cells
ScienCentral.com, April 29, 2005
AIDS researchers may have a new clue about how to keep HIV at bay. As this ScienCentral News video reports, they've discovered how our own cells can repel the virus... MORE
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Technique Shows Promise Against Alzheimer's
By Rick Weiss
Washington Post, April 25, 2005
Injections of genetically altered cells into the brain appear to nourish ailing neurons and may slow the cognitive decline in patients with Alzheimer's disease, scientists reported yesterday in a preliminary study... MORE
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April 15, 2005
A report that aired on “One Life,” a KMTP-TV (local channel 32) series dealing with HIV/AIDS issues, featuring an interview with Eric Verdin discussing HIV latency
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Study describes how HIV beats body's defenses
Virus moves in as T-cells drop protein shields
By Sabin Russell
San Francisco Chronicle, April 14, 2005
Scientists in San Francisco have apparently cracked a 20-year-old mystery surrounding the complex relationship between the AIDS virus and the immune system. In a paper released Wednesday in the online edition of the British journal Nature, UCSF researchers at the Gladstone Institute of Virology and Immunology... MORE
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Study offers new tools in fight against HIV
By Marisa Lagos
The Examiner, April 14, 2005
A study published today by UC San Francisco's Dr. Warner Greene may lead to new therapies for HIV and AIDS. Dr. Greene, director of the UCSF-affiliated Gladstone Institute of Virology and Immunology, and his laboratory discovered why some CD4 T-cells (the main target of HIV) are able to fend off the virus... MORE
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S.F. leads race to be stem cell home base
San Jose, L.A. plan to challenge their disqualifications
By Dave Murphy and Ilene Lelchuk
San Francisco Chronicle, April 13, 2005
San Francisco took the lead Tuesday in the competition to land California's new stem cell institute headquarters, but that position may shift this morning... MORE
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Warner C. Greene, MD, PhD, talks about using the A3G 'antiviral shield' against HIV
By Marc
Strassman
Etopia Media Medical News Network, April 13, 2005
Warner C. Greene is the Director of the Gladstone Institute of Virology and Immunology, a research center dedicated to virology studies, with a focus on HIV and AIDS. He is the senior author of a study due to be posted online today by the British magazine Nature that provides a clearer picture than ever before of why HIV can infect activated CD4 T-cells but cannot infect resting CD4 T-cells... MORE |
Who gets stem cell funding is the $3 Billion Question
Bay Area scientists studying Alzheimer's, sickle cell anemia among those seeking cash
By Rebecca Vesely
Oakland Tribune, April 10, 2005
Bernardo Fernandez Jr. saved his sister's life the day he was born. It's quite a feat for such a little boy, one that gives him great pride four years later... MORE |
AIDS Superinfection
ScienCentral.com, March 29, 2005
Researchers are worried that is possible to become infected with multiple HIV strains, a problem they call 'superinfection.' This ScienCentral News video explains... MORE |
Robotic microscope: a tinker's breakthrough
Neural disease researcher melds optics and computer software
By Sabin Russell
San Francisco Chronicle, March 28, 2005
Dr. Steven Finkbeiner's microscope is one of a kind. It occupies a small room–the size of a large closet–down a hallway humming with refrigerators, freezers and centrifuges at the new laboratory headquarters of the Gladstone Institute of Neurological Disease at Mission Bay in San Francisco. By all appearances, it is a standard Nikon laboratory microscope... MORE |
Real Estate Deals of the Year
Best New Office R&D Development/San Francisco
By Daniel S. Levine
San Francisco Business Times, March 25, 2005
In 1998, before the first shovels of dirt were dug at the University of California at San Francisco's Mission Bay campus, Robert Mahley was making plans to stake a claim alongside it. At the time Mahley, president of the J. David Gladstone Institutes, was wrestling with a problem of future growth. The independent affiliate of UCSF focuses on cardiovascular disease, neurological disease and virology and immunology... MORE |
Drawing a GenMAPP for Biological Pathways
By Bill Schu
Genomics & Proteomics, March 23, 2005
To help biologists understand genomic and proteomic pathways, researchers at the Gladstone Institute of Cardiovascular Disease created GenMAPP. The software is more of a stepping stone than a revolution, which is exactly what developer Bruce Conklin had in mind... MORE |
How the City Secured Solid Offer for Stem Cell Institute
By Rachel Gordon
San Francisco Chronicle, March 18, 2005
San Francisco Mayor Gavin Newsom knew that if the city was going be in the running to land the state's new stem cell institute headquarters, offering rent-free office space would be key. And for a long time, the prospect looked bleak. But last Friday––just days before the bids to the site-selection committee were due––a deal was quietly struck... MORE |
Blackburn Explains Award-winning Research
By Lisa Cisneros
UCSF Today, March 16, 2005
About 200 people gathered recently at the Gladstone Institutes to hear UCSF microbiologist Elizabeth H. Blackburn give an update on her groundbreaking research on the roles of telomeres and telomerase in health and disease. Blackburn delivered the 2005 Gladstone Distinguished Lecture in Molecular and Cell Biology on March 7... MORE
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March 15, 2005
A report that aired on “One Life,” a KMTP-TV (local channel 32) series dealing with HIV/AIDS issues, featuring an interview with Warner Greene discussing HIV and STDs
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Movers
Nature.com, March 3, 2005
An overnight sailing trip helped Deepak Srivastava to plot a course for his scientific career. Brad Thompson, his mentor at medical school, took the newly minted MD out on his boat to celebrate Srivastava's graduation. The dark calm of the night sea provided Srivastava with an opportunity to chart his future... MORE
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Best Places to Work for Postdocs: 2005
By Maria W. Anderson
The Scientist, February 14, 2005 (© 2005 The Scientist)
Five government organizations, four universities, three private institutes, two cancer centers, and one hospital. Those are the U.S. institutions that landed in the top 15 slots in The Scientist's Best Places to Work for Postdocs 2005, which is based on a survey of postdocs who rate their own institutions... MORE [PDF]
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A new avenue for cholesterol drugs?
By Sue Goetinck Ambrose
The Dallas Morning News, January 17, 2005
Dallas scientists have discovered two genetic mutations linked to low levels of the “bad” cholesterol, LDL, a finding that could lead to a new class of drugs. “I think the implications are potentially immense,” said Dr. Thomas Bersot, an endocrinologist at the Gladstone Institute of Cardiovascular Disease... MORE
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